摘要
目的:了解我院麻醉药品应用情况及变化趋势,为临床合理用药提供参考。方法:回顾性分析我院2011–2013年麻醉药品的使用情况,采用WHO推荐的限定日剂量(DDD)计算用药频度(DDDs)、日用药金额(DDC),分析药品的销售金额排序序号(B)与DDDs排序序号(A)的比值等方法,对麻醉药品的使用频度、患者使用麻醉药品的平均日费用、用药金额与用药人次数是否同步等情况进行统计学分析。结果:共收集麻醉药品处方4454张,我院三年供应的麻醉药品共涉及10个品种5种剂型,销售金额由2011年的16.46万元降至2013年的9.75万元,呈逐年下降的趋势;除盐酸羟考酮注射液、盐酸布桂嗪注射液的DDDs值逐年上升,阿桔片、枸橼酸芬太尼注射液、枸橼酸舒芬太尼注射液的DDDs值略有波动外,其余各药品的DDDs值均呈逐年下降趋势;DDC值除硫酸吗啡缓释片有较大波动外,磷酸可待因片、阿桔片的DDC值在2013年较高,盐酸羟考酮缓释片的DDC值在2011年较高,其余6个品种的麻醉药品DDC值均无明显变化。结论:医院不断加强对麻醉药品的管理,规范诊疗行为,以及药师的积极干预,对麻醉药品的合理用药起到了积极有效的作用。
Objective： To investigate the application and tendency of narcotic drugs in our hospital and provide reference for rational drug use in clinic. Methods： The application of narcotic drugs in our hospital from 2011 to 2013 was analyzed retrospectively. The DDDs and the daily drug cost （DDC） were calculated by defined daily dose （DDD） recommended by WHO, and the ratio of the ranked number of the sales amount of drug （B） and the ranked number of DDDs （A） was analyzed. The use frequency of narcotic drugs, the average daily cost of patients with narcotic drugs, whether the amount of drugs use and the number of people using the narcotic drugs synchronized or not were analyzed. Results： There were 4454 prescriptions of narcotic drugs involving 10 varieties and 5 kinds of dosage forms. The amount of sales decreased from 164 600 yuan in 2011 to 97 500 yuan in 2013 with declining trend. In addition, the DDDs of oxycodone hydrochloride injection, buciunazine hydrochloride injection increased year by year and the DDDs of platycodon tablets, fentanyl citrate injection and sufentanil citrate injection showed slight fluctuations, while the DDDs of the other drugs showed a declining trend year by year. In addition to the DDC of morphine sulfate sustained-release tablets had a greater volatility, the DDC of codeine phosphate tablets and platycodon tablets showed slightly higher in 2013, the DDC of oxycodone hydrochloride prolonged-release tablets had slightly higher in 2011, the DDC of the other six species of narcotic drugs had not significant change. Conclusion： Strengthening the management of narcotic drugs, standardizing clinical practice behavior, and the active intervention of pharmacists played a positive and effective role in the rational use and standardized management of narcotic drugs.
出处
《中国药物应用与监测》
CAS
2015年第4期242-245,共4页
Chinese Journal of Drug Application and Monitoring
