摘要
目的:探讨输血前后血浆D-二聚体水平作为肿瘤患者输血前后评估指标的临床意义。方法:按输血效果以及输血量和输血次数进行分组,比较输血前后患者血浆D-二聚体含量变化,对检测结果进行统计学分析。结果:143例经输血治疗的肿瘤患者输血后血浆D-二聚体含量均明显增加,输注红细胞2U以上或多次输血的肿瘤患者血浆D-二聚体含量显著增加(P<0.01),具有统计学意义。结论:血浆D-二聚体含量监测可作为肿瘤患者科学、合理输血的循证依据,并以此制定个性化的输血策略。
Objective:To explore the significance of plasma D-dimer level as an evaluation index in the patients with tumor before and after blood transfusion.Method:The samples were obtained from the patients with tumor before and after blood transfusion.The plasma D-dimer level was tested and analyzed according to the blood transfusion effects,total volume and transfusing times.Result:All of 143 cases were detected,and the plasma D-dimer level increased significantly in those patients which received 2units or more and 2times or more of red blood transfusion.Conclusion:The plasma D-dimer level should be regarded as an indication of scientific and reasonable transfusion on the patients with tumor.In order to set up the individual transfusion regimen,the plasma D-dimer should be detected pre-and post transfusion.
出处
《临床血液学杂志(输血与检验)》
CAS
2015年第4期647-648,共2页
Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)
关键词
输血
D-二聚体
肿瘤
循证
输血策略
blood transfusion
D-dimer
tumor
evidence-based
transfusion regimen