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血浆D-二聚体检测在肿瘤患者输血评估中的意义

Signifcance of plasma D-dimer detection in evaluation on patients with tumor before and after blood transfusion
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摘要 目的:探讨输血前后血浆D-二聚体水平作为肿瘤患者输血前后评估指标的临床意义。方法:按输血效果以及输血量和输血次数进行分组,比较输血前后患者血浆D-二聚体含量变化,对检测结果进行统计学分析。结果:143例经输血治疗的肿瘤患者输血后血浆D-二聚体含量均明显增加,输注红细胞2U以上或多次输血的肿瘤患者血浆D-二聚体含量显著增加(P<0.01),具有统计学意义。结论:血浆D-二聚体含量监测可作为肿瘤患者科学、合理输血的循证依据,并以此制定个性化的输血策略。 Objective:To explore the significance of plasma D-dimer level as an evaluation index in the patients with tumor before and after blood transfusion.Method:The samples were obtained from the patients with tumor before and after blood transfusion.The plasma D-dimer level was tested and analyzed according to the blood transfusion effects,total volume and transfusing times.Result:All of 143 cases were detected,and the plasma D-dimer level increased significantly in those patients which received 2units or more and 2times or more of red blood transfusion.Conclusion:The plasma D-dimer level should be regarded as an indication of scientific and reasonable transfusion on the patients with tumor.In order to set up the individual transfusion regimen,the plasma D-dimer should be detected pre-and post transfusion.
出处 《临床血液学杂志(输血与检验)》 CAS 2015年第4期647-648,共2页 Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)
关键词 输血 D-二聚体 肿瘤 循证 输血策略 blood transfusion D-dimer tumor evidence-based transfusion regimen
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