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脂联素与2型糖尿病及糖尿病早期肾病的临床关联研究 被引量:2

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摘要 目的观察并分析糖尿病肾病(DN)与2型糖尿病(T2DM)早期发生和发展与血清脂联素的关系。方法 50例2型糖尿病患者、50例糖尿病肾病患者和50例健康体检者分别为2型糖尿病组、糖尿病肾病组和健康检测对照组,均采用酶联免疫吸附试验(ELISA)进行检测,并进行回顾性试验分析,观察2型糖尿病、糖尿病肾病和脂联素浓度的关系。结果健康体检者体内血清脂联素浓度明显要高于单纯2型糖尿病和糖尿病肾病患者体内的脂联素浓度,差异均具有统计学意义(P<0.05);且2型糖尿病患者血清脂联素浓度明显高于早期糖尿病肾病患者,差异有统计学意义(P<0.05)。结论 2型糖尿病、糖尿病肾病和脂联素浓度的关系紧密,因此针对糖尿病肾病和2型糖尿病的诊断与治疗可以分析脂联素的浓度作为判定依据,以提高治疗效果。
作者 尚祥岭
出处 《中国实用医药》 2015年第21期85-86,共2页 China Practical Medicine
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