摘要
目的探讨直肠癌术后复发的影响因素、治疗及预防方法。方法选择330例直肠癌患者作为研究对象,分析复发例数、部位、影响因素、治疗方法及预后。结果术后随访(2.98±1.22)年,复发共50例;复发组患者年龄、切缘距肿瘤距离、未实施腹腔化疗、解剖部位腹膜返折下、浸润黏膜下层、病理恶性程度高、Dukes分期C-D期、CES-D≥16分与无复发组比较差异有统计学意义(P<0.05)。局部复发再手术治疗36例,基本达到临床根治要求者19例,1年存活34例,3年存活20例。结论直肠癌根治术后存在一定程度复发率,影响因素复杂,应针对复发因素实施相应的措施以减少复发。
Objective To explore the influencing factors and treatment and prevention methods of the postoperative re- currence after rectal cancer surgery. Methods A total of 330 patients were selected as the study subjects and the num- ber of recurrent patients, location, influencing factors, treatment methods and prognosis were analyzed. Results After （2.98±1.22） years of follow-up visit after surgery, the disease recurred in 50 patients. The age, incisal edge to tumor distance, non-implementation of peritoneal chemotherapy, peritoneal reflex of anatomic site, infiltration of submucosa, severer pathological degree, stage C-D of Dukes staging and CES-D ≥ 16 scores had significant differences between the recurrence group and the non-recurrence group（P〈0.05）. Thirty-six patients received resurgery, of which 19 patients reached clinically radical treatment requirements, 34 patients survived 1 year and 20 patients survived 3 years. Con- clusion There exists recurrence after rectal cancer surgery, of which the influencing factors are complicated. Corre- sponding measures aiming at the recurrence factors should be taken to reduce the recurrence.
出处
《中国现代医生》
2015年第21期1-3,7,共4页
China Modern Doctor
基金
浙江省自然科学基金资助项目(LY13H030005)
关键词
直肠癌
术后复发
影响因素
预防
Rectal cancer
Postoperative recurrence
Influencing factor
Prevention
