摘要
目的观察七叶皂苷配合早期综合干预治疗骨科创伤及其术后肿胀的疗效及安全性。方法将84例骨科创伤患者随机分为对照组和观察组,各42例。两组患者均予以常规联合甘露醇脱水治疗,同时均予以早期综合干预,观察组患者加用七叶皂苷注射液,观察两组患者治疗前后患处冠状面周长及视觉模拟评分法(VAS)评分变化情况,同时评价疗效。结果治疗后,两组患者患肢肿胀部位周长均较治疗前明显减少(P<0.05),且观察组减少更明显(P<0.05);观察组患者治疗总有效率为73.81%,显著高于对照组的66.67%(P<0.05);两组患者治疗后疼痛指数均较治疗前显著下降(P<0.05);两组患者不良反应发生率未见明显差异(P>0.05)。结论七叶皂苷配合早期综合干预对骨科创伤及其术后肿胀的疗效确切。
Objective To observe tbe effect and safety of aescine combined witb early comprebensive intervention in tbe treatment of or-tbopedics trauma and postoperative swelling. Methods Totally 84 patients witb ortbopedics truma were randomly divided into tbe control group and tbe observation group,42 cases in eacb group. Tbe two groups were given routine treatment combined witb mannitol debydra-tion tberapy and early comprebensive intervention,and tbe observation group was added witb tbe aescine injection. Tbe perimeter of swollen part and tbe cbanges of visual analogue scale（VAS）assessment before and after treatment of tbe two groups were observed,and tbe effects were evaluated . Results Tbe perimeter of swollen part in tbe two groups after treatment were obviously de creased （ P 〈 0. 05）,and tbe decease in tbe observation group was more significant（ P 〈 0. 05）;tbe total effective rate of tbe observation group was 73. 81%,wbicb was significantly bigber tban 66. 67% of tbe control group（ P 〈 0. 05）;tbe VAS scores of tbe two group decreased significantly compared witb before treatment（ P 〈 0. 05 ）;tbe adverse reactions of tbe two groups bad no significant difference （ P 〉 0. 05）. Conclusion Tbe effect of aescine combined witb early comprebensive intervention in tbe treatment of ortbopedics trauma and postoperative swelling is clear and effective.
出处
《中国药业》
CAS
2015年第16期143-144,共2页
China Pharmaceuticals
关键词
七叶皂苷
早期综合干预
骨科创伤
肿胀
aescine
early comprebensive intervention
ortbopedics trauma
swelling
