摘要
目的观察旋覆代赭汤加味治疗肝胃郁热型反流性食管炎(RE)的临床疗效。方法将120例肝胃郁热型RE患者随机分为2组,治疗组60例予旋覆代赭汤加味治疗,对照组60例予奥美拉唑镁肠溶片治疗,2组均治疗8周,观察中医证候疗效、胃镜疗效、治疗前后症状积分变化及血清胃动素(MTL)含量。结果治疗组中医证候疗效、胃镜疗效均优于对照组(P<0.05);2组治疗后症状积分均较本组治疗前降低(P<0.05),且治疗组治疗后烧心、胸痛症状积分低于对照组(P<0.05);2组治疗后血清MTL水平均较本组治疗前升高(P<0.05),且治疗组血清MTL水平高于对照组(P<0.05)。结论旋覆代赭汤加味治疗肝胃郁热型RE疗效确切。
Objective To observe the clinical effects of additional Xuanfu - daizhe decoction on reflux esophagitis ( RE ) with liver - stomach heat type. Methods 120 RE patients with liver - stomach heat type were ran- domly divided into two groups. 60 patients in treatment group were treated by additional Xuanfu - daizhe decoction. 60 patients in control group were treated by omeprazole magnesium enteric - coated tablets. The course was eight weeks in two groups. The curative effects of traditional Chinese medicine ( TCM ) symptom and gastroscope, the changes of symptom score and the contents of serum motihn(MTL) before and after treatment were observed in two groups. Re- suits The curative effects of TCM symptom and gastroscope in treatment group were superior to those in control group(P 〈0.05). The symptom score after treatment was decreased in two groups(P 〈 0.05), and the integrals of heartburn and chest pain after treatment in treatment group were lower than those in control group ( P 〈 0.05 ). The level of serum MTL after treatment was increased in two groups (P 〈 0.05 ), and the increase in treatment group was superior to that in control group (P 〈 0.05 ). Conclusion Additional Xuanfu - daizhe decoction has an exact effect on the treatment of reflux esophagitis with liver - stomach heat type.
出处
《河北中医》
2015年第7期1035-1038,共4页
Hebei Journal of Traditional Chinese Medicine
基金
2012年河北省科学技术研究与发展计划项目(编号:12277788)
关键词
辨证分型
食管炎
消化性
旋覆代赭汤
中医药疗法
Sydrome differentiation
Peptic esophagitis
Xuanfu - daizhe decoction
Traditional Chinese medicine therapy