摘要
目的:为围术期合理使用血凝酶类药物提供参考。方法:采用回顾性方法,随机抽取我院2014年1-12月围术期预防使用血凝酶类止血药患者的出院病历1 200份,对血凝酶类药物的消耗量、消耗金额、各科室使用情况、不合理用药情况等进行统计分析。结果:血凝酶类药物金额占住院用药总金额的7.39%,其中注射用尖吻蝮蛇血凝酶的消耗量和消耗金额最高,使用率为51.44%。各科室围术期血凝酶类药物平均用药天数为2.36d,耳鼻咽喉-头颈外科/口腔科的平均血凝酶类药物费用最高为684.52元;耳鼻咽喉-头颈外科/口腔科、泌尿外科平均用药时间较长,分别为3.85、3.50d。围术期预防用血凝酶类药物的合理使用率仅为39.42%,其不合理情况主要表现为用药时机不当(52.15%)、术后用药时间过长(35.75%)、用法错误(5.61%)、无理由更换多种血凝酶类药物(5.06%)。结论:围术期血凝酶类药物不合理的使用现状令人堪忧,需要加强规范化的管理,同时加大临床药师的药学监督及干预措施。
OBJECTIVE：To provide reference for the rational use of haemocoagulase hemostatic drugs in the clinic by understanding the perioperative utilization. METHODS：In retrospective study,1 200 discharge records of perioperative prophylactic application of haemocoagulase hemostatic drugs were collected randomly during Jan.-Dec. 2014.,and then analyzed statistically in respects of consumption sum and amount,application,irrational drug use,etc. The cost of hemocoagulase accounted for 7.39% of total drug cost,among which Haemocoagulase agkistrodon for injection had the highest consumption amount and sum,with utilization ratio of 51.44%. Average medication time of hemocoagulase during perioperative period was 2.36d;maximal average cost of hemocoagulase was 684.52 yuan in ENT and head and neck surgery department/ stomatology department;ENT and head and neck surgery department/ stomatology department,urinary surgery department had long average medication time,being 3.85 d and 3.50 d.RESULTS：Only 39.42% haemocoagulase hemostatic drugs were reasonably used during perioperative period. The unreasonable manifestation included：improper medication time（52.15%）, too long medication course after operation（35.75%）,wrong usage（5.61%）and replacing various haemocoagulase hemostatic drugs without reason（5.06%）. CONCLUSIONS：The striking phenomenon of irrational use of haemocoagulase hemostatic drugs during perioperative period is severely worrying,so we need to strengthen the standard management and pharmaceutical supervision and intervention by clinical pharmacists.
出处
《中国药房》
CAS
北大核心
2015年第23期3195-3197,共3页
China Pharmacy
关键词
血凝酶类药物
围术期
预防用药
合理用药
Haemocoagulase hemostatic drugs
Perioperative period
Prophylactic application of drugs
Reasonable drug use
