摘要
目的探讨多层螺旋CT(MSCT)联合检测血清C反应蛋白(CRP)、纤维蛋白原(FIB)对老年结肠癌患者术前评估的临床意义。方法前瞻性纳入108例老年结肠癌患者,随机分为观察组和对照组各54例,对术前分期及术式预测分别与术后病理分期及实际手术方案进行比较。结果观察组术前T、N、M及TNM分期准确度分别为75.93%、87.04%、100%、85.19%,对照组分别为61.11%、66.67%、94.44%、68.52%,观察组术前N、TNM分期的准确度明显高于对照组,差异均有统计学意义(χ2=6.30、4.22,P均<0.05),两组T、M分期比较,差异无统计学意义(χ2分别=2.75、3.09,P均>0.05);观察组手术方案预测符合率92.59%高于对照组77.78%,差异有统计学意义(χ2=4.70,P<0.05)。结论 MSCT联合CRP对于老年结肠癌患者术前N、TNM分期及手术方案预测优于MSCT联合FIB。
Objective To explore the clinical significance of preoperative assessment of multi-slice spiral CT scan com-bined with serum C-reactive protein（CRP） and fibrinogen（FIB） in elderly with colon cancer. Methods A total of 108 elderly with colon cancer were enrolled and divided into observation group which underwent MSCT combined with CRP as-sessment and the control group which received preoperative SCT combined with FIB. 54 cases in each group, the staging and surgical planning were compared between pre-operation and post-operation. Results The accuracies of T, N, M and TNM staging pre-operation were 75.93%, 87.04%, 100%, 85.19% in observation group and 61.11%, 66.67%, 94.44%,68.52% in control group. The accuracies of N, TNM staging in observation group was significantly higher than control group（χ2=6.30, 4.22, P〉0.05）. The differences of accuracies of T, M staging was not statistically significant（χ2=2.75,3.09, P〈0.05）. The rate of surgery program in line with forecast in the observation group was 92.59%,which was higher than the 77.78% in control group（χ2=4.70, P〈0.05）. Conclusion The MSCT combined with CRP preoperative assessment on elderly with colon cancer is better than combined with FIB.
出处
《全科医学临床与教育》
2015年第4期410-412,共3页
Clinical Education of General Practice
