摘要
目的:探讨64排多层螺旋CT(MSCT)联合炎症因子血清C反应蛋白(CRP)术前评估结肠癌的临床价值和对手术方案选择的影响。方法:将2011年1月—2011年12月于我院胃肠外科住院的96例结肠癌患者随机均分为A组和B组,A组术前行MSCT和CRP联合评估,B组只进行MSCT评估,对术前分期和预测手术方案与术后病理分期和实际手术方案进行比较。结果:本研究实际纳入病例90例,A组45例,B组45例,两组基线情况一致。A组术前T、N、M及TNM分期的准确度分别为71.1%、86.7%、97.8%及84.4%;B组术前T、N、M及TNM分期的准确度分别为66.7%、66.7%、95.5%及66.7%。A组和B组在N、TNM分期的差异有统计学意义(P=0.013、P=0.023)。A组手术符合率为97.8%(44/45),B组手术符合率为86.7%(39/45),两组间预测符合率差异具有统计学意义(P=0.037)。结论:MSCT联合CRP评估结肠癌患者的策略可以提高术前分期的准确性和手术预测方案的符合率。
Objective：To discuss the influence of combination of 64 multi-slice spiral computer tomography（MSCT） and C-reactive protein（CRP） for the preoperative assessment of colon cancers.Methods：Data from 96 patients with definitive diagnoses of colon cancer from January 2011 to december 2011 were studied prospectively and randomly assigned into Groups A and B,respectively.Both MSCT and CRP combinative assessments were made for preoperative evaluation in Group A,whereas only MSCT was performed preoperatively in Group B.Furthermore,the preoperative staging and prediction of operative procedures were compared with postoperative pathologic staging and practical operative procedures,respectively.Results：According to inclusion criteria,90 colon cancer patients were included in Group A（n=45） and in Group B（n=45）.The baseline characteristics of the two groups were statistically identical.For Group A,the accuracy of the preoperative T,N,M,and TNM staging were 71.1%,86.7%,97.8%,and 84.4%,respectively.For Group B,the corresponding rates were 66.7%,66.7%,95.5%,and 66.7%,respectively.The difference in accuracy between the N and TNM staging between the two groups was observed statistically（P=0.013 and P=0.023,respectively）.There was also a statistically significant difference in the accuracy of prediction of operative procedures be-tween Groups A and B（97.8% vs 86.7%,P=0.037）.Conclusion：The combinative assessment of colon cancer using MSCT and CRP could improve the accuracy of preoperative staging and the accurate prediction of surgical strategy in colon cancer.
出处
《中国现代普通外科进展》
CAS
2012年第7期533-536,共4页
Chinese Journal of Current Advances in General Surgery
关键词
结肠肿瘤
术前分期
多层螺旋CT
CRP
Colonic neoplasm
Preoperative stage
Multi-slice spiral computer tomography· C reactive protein
