摘要
Ki-67在临床上具有重要的应用价值,但其表达阳性率临界值的界定尚存有争议,给临床应用带来一定困难.本文总结了国内外在Ki-67对乳腺癌预后判断、临床指导治疗价值及其表 达阳性率临界值界定的研究,分析了各项研究存在差异的原因,并提出科学界定Ki-67表达阳性率临界值的必要性及临床重要性,从而为Ki-67在临床应用提供一定的理论依据.
Ki-67 has an important application value in clinical practice.However,it is still a little tough in clinical application because of the debate on the cut-off definition of Ki-67 index.This review summarizes most studies on the prognostic and predictive value of Ki-67,analyzes the reasons for the discrepancies among the studies cited,and presents the necessity and clinical significance of scientifically defining the cut-off of Ki-67 index,providing a theoretical basis for Ki-67 in clinical application.
出处
《中华外科杂志》
CAS
CSCD
北大核心
2015年第8期634-637,共4页
Chinese Journal of Surgery
