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抑肝散治疗痴呆症的临床及实验研究现状 被引量:5

Research status of Yigansan in the treatment of dementia
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摘要 痴呆是一种严重影响人类健康的疾病,如何防治痴呆已成为医学界的研究热点。临床及实验研究提示,抑肝散可以改善痴呆患者的行为心理学症状,同时其作用机制多样。本文综述了抑肝散治疗痴呆的临床及实验现状,为进一步合理开发和利用抑肝散提供理论依据。 Dementia has affected health severally, and the preventions and treatments of dementia have attracted common attention recently. Yigansan is effective for the behavioral and psychological symptoms of dementia patients through various mechanisms in both pre-clinical and clinical studies. In this review, the latest clinic and experimental studies on dementia treatment of Yigansan are illustrated, which provides a theoretical basis for further development and utilization of Yigansan.
出处 《中国医药导报》 CAS 2015年第22期40-42,共3页 China Medical Herald
基金 教育部"春晖计划"合作科研项目(Z2010018)
关键词 痴呆 动物模型 复方治疗 抑肝散 Dementia Animal model Compound therapy Yigansan
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  • 1Mizukami K,Asada T,Kinoshita T,et al. A randomized cross-over study of a traditional Japanese medicine(kam- po),yokukansan,in the treatment of the behavioural and psychological symptoms of dementia [J]. Int J Neuropsy- cho-pharmacol, 2009,1.2(2) : 191-199. 被引量:1
  • 2Iwasaki K, Satoh-Nakagawa T, Maruyama M, et al. A ran- domized,observer-blind,controlled trial of the traditional Chinese medicine Yi-Gan San for improvement of behav- ioral and psychological symptoms and activities of daily living in dementia patients [J]. J Clin Psychiatry, 2005,66 (2) :248-252. 被引量:1
  • 3Monji A,Takita M,Samejima T,et al. Effect of yokukans anon the behavioral and psychological symptoms of demen- tia inelderly patients with Alzheimer's disease [J]. Prog Neu- ropsy-chopharmacol Biol Psychiatry, 2009,33 ( 2 ) : 308-311. 被引量:1
  • 4Okahara K,Ishida Y,Hayashi Y,et al. Effects of Yokukansan on behavioral and psychological symptoms of dementia in regular treatment for Alzheimer's disease [J]. Prog Neu- ropsychopharmacol Biol Psychiatry,2010,34(3) :532-536. 被引量:1
  • 5Kimura T, Hayashida H,Furukawa H, et al. Pilot study of pharmacological treatment for frontotemporal dementia:ef- fect of Yokukansan on behavioral symptoms [J]. Psychiatry Clin Neurosci, 2010,64 (2) : 207-210. 被引量:1
  • 6Ognibene E, Middei S, Daniele S, et al. Aspects of spatial memory and behavioral disinhibition in Tg2576 transgenic mice as a model of Alzheimer's disease [J]. Behav Brain Res, 2005,156(2) : 225-232. 被引量:1
  • 7Tabuchi M, Yamaguchi T, Iizuka S, et al. Ameliorative ef- fects of yokukansan,a traditional Japanese medicine,on learning and non-cognitive disturbances in the Tg2576 mouse model of Alzheimer's disease [J]. J Ethnopharmacol, 2009,122( 1 ) : 157-162. 被引量:1
  • 8Fujiwara H,Takayama S,Iwasaki K,et al. Yokukansan,a traditional Japanese medicine,ameliorates memory distur- bance and abnormal social interaction with anti-aggrega- tion effect of cerebral amyloid b proteins inamyloid precur- sor protein transgenic mice [J]. Neuroscience,20111 (180) : 305-313. 被引量:1
  • 9Fujiwara H,Iwasaki K,Furukawa K,et al. Uncaria rhyn- chophylla, a Chinese medicinal herb, has potent antiaggre- gation effects on Alzheimer's b-amyloidproteins [J]. J Neu- rosci Res, 2006,84(2) : 427-433. 被引量:1
  • 10Calingasan NY, Gandy SE, Baker H,et al. Accumulation of amyloid precursor protein-like immunoreactivity in rat brain in response to thiamine deficiency [J]. Brain Res, 1995,677( 1 ) : 50-60. 被引量:1

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