摘要
目的探讨慢性稳定性心绞痛患者冠状动脉临界病变血管内超声斑块影像学特征。方法对慢性稳定性心绞痛患者行冠状动脉造影检查,对冠状动脉造影显示为临界病变者,行血管内超声检查,评估斑块特征。结果 163例冠状动脉临界病变患者中薄帽纤维粥样硬化斑块(TCFA)、厚帽纤维粥样硬化斑块(ThCFA)患者分别为37、50例。TCFA、ThCFA患者临床特征、冠状动脉分布情况差异无统计学意义;超过50%的临界病变血管在左冠状动脉前降支;ThCFA患者平均斑块负荷、斑块面积高于TCFA患者;ThCFA及TCFA患者斑块成分以纤维组织最多,其次为纤维脂肪组织和坏死核心成分,高密度钙化面积最低。TCFA患者最小管腔面积≤4.0mm2者占18.92%(7/37),显著高于ThCFA患者。结论慢性稳定性心绞痛冠状动脉临界病变ThCFA患者斑块负荷更重,管腔面积更大。TCFA患者最小管腔面积≤4.0mm2比例更高。
Objective To explore the characteristics of intravascular ultrasound-virtual histology （IVUS-VH） on patients with intermediate severity coronary lesions of chronic stable angina. Methods Patients with intermediate severity coronary lesions of chronic stable angina confirmed by coronary angiography underwent IVUS-VH, and the characteristics were analyzed. Results Totally 163 patients with intermediate severity coronary lesions, of which 37 patients were thin-cap fibroatheroma （TCFA） and 50 patients were thick-cap fibroatheroma （ThCFA）. The clinical characteristics and coronary distribution between TCFA and ThCFA patients had no difference （P〉0.05）. More than 50% lesion distributed at anterior descending branch. Compared with ThCFA patients, plaque burden and plaque area were lower in TCFA patients. IVUS-VH showed descending order of TCFA and ThCFA components were fibrotie, fibrofatty and necrotic core, dense calcium. Min- imum lumen area ≤4.0 mm^2 of TCFA patients accounted for 18.92% （7/37）, significantly higher than that in ThCFA patients. Conclusion Patients with TCFA intermediate severity coronary lesions of chronic stable angina have more serious plaque burden and larger lumen area; proportion of TCFA patients with minimal lumen area ≤4.0 mm^2 are higher.
出处
《中国介入影像与治疗学》
CSCD
北大核心
2015年第8期484-488,共5页
Chinese Journal of Interventional Imaging and Therapy
基金
上海市浦东新区卫生和计划生育委员会科技发展专项基金(PW2013A-26)
上海市浦东新区卫生和计划生育委员会行业专项基金(PW2013E-2)
上海市浦东新区卫生和计划生育委员会重点学科建设基金(PDZx2014-01)
关键词
心绞痛
超声检查
冠状动脉疾病
诊断显像
Angina pectoris
Ultrasonography
Coronary disease
Diagnostic imaging
