摘要
目的研究不同T分期与N分期中采用同期放化疗治疗对鼻咽癌患者的临床疗效。方法选择132例鼻咽癌患者为研究对象,均在2014年10月完成所有治疗及随访,采用对照研究的方式将其分为两组,T分期组(60例)和N分期组(72例);均行放化同期治疗,对两组患者的临床疗效及不良反应进行归纳总结。结果两组患者各项并发症发生率无明显差异;T分期组患者治疗总有效率为80.0%,N分期组患者治疗总有效率为84.7%;两组患者在复发率、转移率、复发并转移率、3年生存率及5年生存率的比较上χ2=7.31、10.43、7.74、4.95、4.48,P均<0.05,差异具有统计学意义。结论鼻咽癌患者采用放化同期治疗,其病情的预后和转归与N分期和T分期具有相关性,但N分期为主导因素,对患者行分层放疗可有助于提高临床疗效。
Objective Objective This paper is to study clinical efficacy of mere radiotherapy applied to treat patients with nasopharyngeal carcinoma at sub-stage T and sub-stage N. MethodsOne hundred and thirty two patients with nasopharyngeal carcinoma（NPC） were selected as research subjects, all of those patients completed the treatment and followup as of October, 2014, and the manner of control study was applied to divide them into two groups with 60 patients at T sub-stage group and 72 patients in N sub-stage group, patients in two groups were subject mere radiotherapy treatment, clinical efficacy and adverse effects of patients in two groups were summarized. Results There was no significant difference in the rate of complications of patients in two groups, the total effective rate of patients in T sub-stage group and N sub-stage group hit 80% and 84.7% respectively, the comparison in the recurrence rate, metastasis rate, rate of recurrence and metastasis, three-year survival rate and five-year survival rate hit χ2=7.31, 10.43, 7.74, 10.43 and 7.74 respectively with average P0.05, and the difference was statistically significant. Conclusion Mere radiotherapy applied on patients with nasopharyngeal carcinoma delivers efficacy, the prognosis and outcome of illness are associated with N sub-stage and T sub-stage, while the N sub-stage serves as the leading factor, and stratified radiotherapy can facilitate improving clinical efficacy of patients.
出处
《中国CT和MRI杂志》
2015年第8期17-19,39,共4页
Chinese Journal of CT and MRI
关键词
鼻咽癌
T分期
N分期
放化同期
临床疗效
Nasopharyngeal Carcinoma
T Sub-stage
N Sub-stage
Mere Radiotherapy
Clinical Efficacy
