摘要
目的：探讨江苏省阜宁县50岁及以上人群中前房角关闭的患病率特征。方法于2010年3～5月，采取整群随机抽样法在阜宁县调查了5202例，应用Van Herick法对受检人群进行周边前房深度检查初筛，对其中周边前房深度≤1/3角膜厚度者进行前房角镜检查，确定为解剖的窄前房角者再进行明、暗光线下超声活体显微镜（UBM）检查，分别观察受检眼上方、颞上方、颞侧、颞下方、下方、鼻下方、鼻侧和鼻上方8个检查部位有无前房角关闭，评估具有解剖的窄前房角患眼前房角关闭率。从UBM图像中测量前房角开放距离。明、暗光线下前房角关闭率比较采用配对χ2检验，前房角开放距离的比较采用配对t检验。结果经Van Herick法初筛出347例浅前房患者，完成全部检查的共有243例（484只眼）患者。以受检眼计算，在明、暗光线下UBM检查发现的前房角关闭率分别为24.0%和69.6%，显示暗光线下前房角关闭率明显增高，两者间差异有统计学意义（χ2=204.36，P〈0.001）。明光线下以鼻上方最高，为14.3%，暗光线下以上方的前房角关闭率最高，为42.8%。明或暗光线下，8个检查部位之间前房角开放距离的差异均有统计学意义（t=6.039，6.883，11.612，11.157，4.732，6.798，5.156，4.071；P〈0.001）。按受检者暗光线UBM检查下前房角关闭率81.07%估计，阜宁县50岁及以上人群前房角关闭率为5.40%（95%CI：4.80%～6.05%）。结论本调查人群的前房角关闭患病率高于以往调查结果，这可能与本研究采取的检查方法，即UBM暗光线下检查前房角能够早期筛查前房角关闭患者有关。（中华眼科杂志，2015，51：487-492）
Objective The purpose of the study is to determine the prevalence of appositional angle closure in persons aged 50 or above in Funing County. Methods Cluster sampling randomly selected residents in Funing County aged 50 years or above. From March to May 2010, 484 eyes of 243 patients with the shallow peripheral anterior chamber and the anatomic narrow chamber angle, which was determined by Van Herick technique and gonioscopy, were collected from 5202 individuals. The presence of appositional angle closure and the angle-opening distance（AOD） was determined with photopic and scotopic ultrasound biomicroscopy（UBM） in eight positions. Paired χ2 test and paired t test（SPSS 17.0） were used to determine any significant differences at P〈0.05. Results The prevalence of appositional angle closure was found at least one position in 337 eyes（69.6%） by scotopic UBM and in 116 eyes（24.0%） by photopic UBM. The prevalence of appositional angle closure was significantly higher by scotopic UBM than by photopic UBM（χ2=204.36, P〈0.001 respectively）, and was the highest in superior quadrant. The AOD varied significantly among the eight positions and was significantly narrower by scotopic UBM than by photopic UBM （t=6.039, 6.883, 11.612, 11.157, 4.732, 6.798, 5.156, 4.071; P〈0.001）. Since 197 persons（81.07%） were found anterior angle closure by scotopic UBM, we estimated the prevalence of appositional angle closure was 5.40 %（95%CI： 4.80%-6.05%）among adults aged 50 or above in Funing County. Conclusions The prevalence of appositional angle closure was higher than previous surveys, the possible reason is that scotopic＆nbsp;UBM could find early appositional angle closure more preferably.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2015年第7期487-492,共6页
Chinese Journal of Ophthalmology
关键词
青光眼
闭角型
患病率
抽样研究
Glaucoma,angle-closure
Prevalence
Sampling studies
