摘要
目的研究医院感染患者病原学标本送检与抗菌药物使用的相关性,探讨抗菌药物使用的合理性。方法通过回顾性调查方式,对某医院8 775例临床治疗性使用抗菌药物的患者病原学标本送检与检验结果情况进行分析。结果该医院住院患者抗菌药物平均使用率为51.09%,治疗性用药构成比占56.93%,病原学标本平均送检率为66.36%。2013年治疗性用药比例和病原学标本送检率均较2012年有所提高。治疗性使用抗菌药物患者标本病原菌检出居前3位为大肠埃希菌、肺炎克雷伯菌和铜绿假单胞菌。治疗性使用抗菌药物频率由高至低依次为三代头孢菌素类、β-内酰胺酶抑制、氨基糖阿甘类、碳青霉烯类和氟喹诺酮类。结论该医院住院患者抗菌药物使用处于较合理的状态,病原学标本送检符合相关规范要求。
Objective To observe the correlation between pathogenic inspection and antimicrobial use in patients with hospital infection and to discuss the rationality in using antibacterial drugs. Methods Through the retrospective investigation, the pathogenic inspection and test results in 8 775 cases of patients with clinical therapeutic use of antimicrobial drugs in a hospital were investigated and analyzed. Results The total antibiotics use of inpatients was 51.09% on average, therapeutic use in patients was more than 56. 93% ,and pathogenic specimens inspection rate was 66. 36% on average. In year 2013 therapeutic use proportions and pathology specimens sent rate increased compared with 2012. The top three pathogens detected from patients with clinical therapeutic use of antimicrobial drugs were Escherichia coil ,KlebsieUa pneumoniae and Pseudomonas acraginosa. The most frequently therapeutic use of antimicrobial drugs was three generation Cephalosporin class ,followed by Beta lactamase inhibition,Amino sugar forrest gump, Carbapenems and Fluoroquinolone, Conclusion The hospital inpatients with antimierobial drug use is reasonable, and pathogenic specimens inspection is accord with the relevant codes.
出处
《中国消毒学杂志》
CAS
北大核心
2015年第7期669-671,共3页
Chinese Journal of Disinfection
基金
辽宁省自然科学基金项目(2013225305)
关键词
抗菌药物
合理使用
病原学标本
送检率
antibacterial drugs
rational use
pathogenic specimen
inspection rate
