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老年人调脂药物与其他常用药物的相互作用 被引量:4

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摘要 随着年龄增长,老年人机体各脏器、组织结构及其生理功能逐渐出现退行性改变,尤其是肝、肾功能的衰退,对药物的吸收、分布、代谢和排泄以及对药物的敏感性和耐受性均发生变化。老年人往往同时罹患多种疾病,需同时服用多种药物,而这些药物之间易发生相互作用。因此,应充分认识老年人的上述特点,严格掌握用药原则,及时调整药物剂量,密切监测,以提高药物疗效,将药物的不良反应降至最低[1-3]。
出处 《中国医学前沿杂志(电子版)》 2015年第5期12-15,共4页 Chinese Journal of the Frontiers of Medical Science(Electronic Version)
基金 国家科技支撑计划(2012BAI37B05)
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  • 1中国成人血脂异常防治指南[J].中华心血管病杂志,2007,35(5):390-419. 被引量:5223
  • 2中国成人血脂异常防治指南制定联合委员会.中国成人血脂异常防治指南.中华心血管病杂志,2001,29:315-317. 被引量:7
  • 3Stone NJ,Robinson J,Lichtenstein AH,et al.2013 ACC/AHA Guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults:a report of the American College of Cardiology/American Heart Association task force on practice guidelines[J].Circulation,2013,pii:S0735-1097 (13)06028-2. 被引量:1
  • 4Scandinavian simvastatin survival study group.Randomised trial of lowering in 4444 patients with coronary heart disease:the Scandinavian simvastatin survival study (4S)[J].Lancet,1994,344:1383-1389. 被引量:1
  • 5Sharp collaborative group.Study of heart and renal protection (SHARP):randomized trial to assess the effects of lowering lowdensity lipoprotein cholesterol among 9438 patients with chronic kidney disease[J].Am Heart J,2010,160:785-794.e10. 被引量:1
  • 6Baigent C,Blackwell L,Emberson J,et al.Efficacy and safety of more intensive lowering of LDL cholesterol:a meta-analysis of data from 170000 participants in 26 randomised trials[J].Lancet,2010,376:1670-1681. 被引量:1
  • 7FDA Drug Safety Communication:New restrictions,contraindications,and dose limitations for Zocor (simvastatin) to reduce the risk of muscle injury[EB/OL].(2011-06-08)[2014-03-27].http://www.fda.gov/Drugs/DrugSafety/ucm256581.htm. 被引量:1
  • 8The National Lipid Association recommendations for patientcentered treatment of dyslipidemia[EB/OL].(2014-05-20)[2014-05-21].https://www.lipid.org/nla/recommendationspatient-centered-management-dyslipidemia. 被引量:1
  • 9Cannon CP,Braunwald E,McCabe CH,et al.Intensive versus moderate lipid lowering with statins after acute coronary syndromes[J].N Engl J Med,2004,350:1495-1504. 被引量:1
  • 10HPS2-THRIVE Collaborative Group.HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant:trial design,pre-specified muscle and liver outcomes,and reasons for stopping study treatment[J].Eur Heart J,2013,34:1279-1291. 被引量:1

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  • 1ABang LM,Goa KL.Pravastatin: a review of its use in elderly patients[J]. Drugs Aging,2003;20(14):1061-1082. PMID: 14651445. 被引量:1
  • 2Hunt D,Young P,Simes J,et al.Benefits of pravastatin on cardiovascular events and mortality in older patients with coronary heart disease are equal to or exceed those seen in younger patients: Results from the LIPID trial[J].Anu Intern Med,2001,134(10):931-940. PMID: 11352694. 被引量:1
  • 3Shepherd J,Blauw GJ,Murphy MB,et al.Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial[J]. Lancet,2002,360(9346):1623-1630. PMID: 12457784. 被引量:1
  • 4Strandberg TE,Kolehmainen L,Vuorio A.Evaluation and treatment of older patients with hypercholesterolemia: a clinical review[J]. JAMA,2014,312(11):1136- 1 144. DOI:10.1001/jama.2014.10924. 被引量:1
  • 5Eaton CB,Lapane KL,Murphy JB,et al.Effect of statin (HMG-Co-A- Reductase Inhibitor) use on 1-year mortality and hospitalization rates in older patients with cardiovascular disease living in nursing homes[J].J Am Geriatr Soc, 2002,50(8):1389-1395. PMID: 12164995. 被引量:1
  • 6Cholesterol Treatment Trialists' (CTT) Collaboration,Baigent C,Blackwell L,et al.Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials[J].Lancet,2010,376(9753):1670-1681. DOI:10.1016/S0140-6736(10)61350-5. 被引量:1
  • 7Sueta CA,Chowdhury M,Boccuzzi SJ,et al.Analysis of the degree of undertreatment of hyperlipidemia and congestive heart failure secondary to coronary artery disease[J].Am J Cardiol,1999,83(9):1303-1307. PMID: 10235085. 被引量:1
  • 8Geleedst-De Vooght M,Maitland-van der Zee AH,Schalekamp T,et ahStatin prescribing in the elderly in the Netherlands: a pharmacy database time trend study[J],Drugs Aging,2010,27(7):589-596. DOI:10.2165/11537330-000000000-00000. 被引量:1
  • 9Markes E, Johnson MA, Wilson JA, et al. Borings in Quartzite Surf Boulders from the UpperCambrian Basal Deadwood Formation, Black Hillsof South Dakota[ J ]. Ichnos ,2010,17 ( 1 ) :48-55. 被引量:1
  • 10Magnus, Ivarsson C, Broman E, et al. Fungal colonization of an Ordo- vician impact-induced hydrothermal system [ J ]. Scientific reports, 2013,3 (25) :3487. 被引量:1

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