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比较尿道前列腺剜除术与电切术治疗前列腺增生的临床疗效分析 被引量:5

Analysis of clinical curative effect comparison enucleation of prostate and transurethral resection of prostate for the treatment of benign prostatic hyperplasia
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摘要 目的探讨分析尿道前列腺剜除术(TUEP)与电切术(TURP)治疗前列腺增生的临床疗效。方法选取前列腺增生患者150例,随机分为TURP组(100例)和TUEP组(50例),其中TURP组采用TULIP术、TUEP组采用TUEP术。记录两组手术时间、术中出血量、切除组织量、留置导尿时间;记录患者术后1、3、5年的相关指标。①患者的前列腺症状评分(IPSS)和生活质量评分(QOL);②血清PSA和口sA、前列腺体积、最大尿流率(Qmax)、残余尿量(PVR);③远期并发症:尿道狭窄、膀胱颈挛缩(BNC)、膀胱颈狭窄,对患者的临床资料进行回顾性分析。结果TURP组和TUEP组患者术中出血量(81.3±11.4mLVS72.1±15.4mL)及切除组织量(47.1±8.7gvs51.6±12.3g)比较,差异均有统计学意义(P〈0.05)。TUVP、PKRP术后1、3、5年患者的IPSS、QOL、Qmax、残余尿量,组间比较均无统计学差异(P〉0.05)。TuRP、TUEP术后1、3、5年血清PSA[(1.88±0.88)、(1.92±0.78)、(1.95±1.01)ug/Lvs(2.08±0.86)、(2.12±0.75)、(2.25±1.11)ug/L],前列腺体积[(42.02±12.46)、(43.12±13.45)、(45.32±16.21)ug/LVS(47.02±12.23)、(48.12±13.54)、(50.32±16.16)mL],组间对应点比较差异均有统计学意义(P〈0.05)。TURP组术后有15例发生继发性出血、1例发生电切综合征。TUEP组术后无患者出现继发性出血和电切综合征,两组患者在膀胱颈挛缩发生率、尿道狭窄发生率、前列腺残留腺体增生发生率、继发性出血发生率、电切综合征发生率比较,差异均有统计学意义(P〈0.05)。结论TUEP术相对于TURP术,对BPH具有相同的理想治疗效果,而且同时具有术中出血少、手术时间短、切除增生组织较彻底等优势,但是TUEP仍存在一些问题,如对术者的熟练度要求较高并且要有一定的� Objectives To investigate the clinical curative effect between enucleation of prostate and transurethral resection of prostate for the treatment of benign prostatic hyperplasia. Methods One hundred and fifty cases of patients with benign prostatic hyperplasia were randomly divided into TURP group (100 cases) and TUEP group (50 cases). Operation time, blood loss in the operation, the resected tissue weight, indwelling catheter time of two groups had been recorded, so was related indexes in patients with postoperative 1, 3,5 years such as the patient prostate symptom score (IPSS) and life quality score (QOL) ;the serum PSA and fPSA, prostate volume, maximum urine flow rate (Qmax), residual urine volume (PVR) ;the long term complications: urethral strieture, bladder neck contracture ( BNC), the bladder neck stenosis,etc. Clinical data of patients was retrospectively analysed. Results The amount of bleeding in group TURP and group TUEP patients (81.3 + 11.4mL vs 72.1 + 15.4mL) and the amount of tissue removed (47.1 + 8.7G vs 51.6 + 12.3 g) has been in comparison, the difference was statistically significant( P 〈0.05). TUVP, PKRP after 1, 3, 5 years in patients with IPSS, QOL, Qmax, residual urine volume, comparison between two groups were not statistically significant( P 〉 0.05 ). TURP and TUEP groups PSA after 1, 3, 5 years [ (1.88 ±0.88) ,(1.92 ±0.78) ,(1.95 ±1.01)ug/L vs (2.08 ±0.86) ,(2.12 ±0.75) ,(2. 25±1.11)ug/L], prostate volume [(42.02 + 12.46), (43.12 + 13.45), (45.32 + 16.21)mLvs (47.02 + 12.23 ) , (48.12 ±13.54), (50.32 + 16.16 ) mL ]. Between group comparison of corresponding points difference had statistical significance( P 〈 0.05 ). TURP group were 15 patients occurred secondary hemorrhage, 1 cases occurred transurethral resection syndrome. No patient had secondary hemorrhage and transurethral resection syndrome after operation in TUEP group, the two groups of patients the in
出处 《国际泌尿系统杂志》 2015年第4期493-497,共5页 International Journal of Urology and Nephrology
关键词 前列腺增生 尿道 电外科手术 Prostatic Hyperplasia Urethra Electrosurgery
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参考文献20

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