摘要
目的分析小剂量叶酸联合维生素B6治疗高同型半胱氨酸合并冠心病的可行性和意义,以改善患者的临床症状并提高预后。方法 100例高同型半胱氨酸合并冠心病患者随机分为对照组和观察组,各50例。对照组患者按照冠心病传统治疗方案进行用药,观察组患者在传统用药方案的基础上联合应用小剂量叶酸和维生素B6,对比用药后两组患者临床治疗效果。结果观察组治疗总有效率96.00%高于对照组的76.00%,两组比较,差异具有统计学意义(P<0.05)。结论高同型半胱氨酸合并冠心病患者给予传统西医药物治疗同时辅以小剂量叶酸和维生素B6,不仅能够降低患者体内半胱氨酸含量并能够显著提高临床治疗效果,提高患者的预后并减少不良事件的发生几率,值得临床应用。
Objective To analyze the feasibility and significance of small dose of folic acid combined with vitamin B6 in the treatment of hyperhomocysteine complicated with coronary heart disease, in order to improve clinical symptoms and their prognosis. Methods There were 100 patients of hyperhomocysteine complicated with coronary heart disease, and they were randomly divided into control group and observation group, with 50 cases in each group. The control group received drug therapy according to traditional treatment scheme for coronary heart disease, and the observation group received additional small dose of folic acid and vitamin B6. Clinical effects in the two groups were compared. Results The observation group had higher total effective rate as 96.00% than 76.00% of the control group, and their difference had statistical significance（P〈0.05）. Conclusion Combination of small dose of folic acid combined with vitamin B6 in addition to traditional Western medicine therapy for hyperhomocysteine complicated with coronary heart disease can remarkably improve clinical effect and prognosis, and reduce incidence of adverse reactions. This method is worthy of clinical application.
出处
《中国实用医药》
2015年第18期51-52,共2页
China Practical Medicine
关键词
冠心病
高同型半胱氨酸
叶酸
维生素B6
Coronary heart disease
Hyperhomocysteine
Folic acid
Vitamin B6
