摘要
目的:探讨药源性高钾血症的特点及相关因素,为临床合理用药提供依据。方法:检索1979-2014年国内医药期刊公开报道的药源性高钾血症的个案和群案文献46篇,共计病例66例,并进行统计分析。结果:66例药源性高钾血症病例中主要涉及心血管药物和免疫抑制剂。大部分停药及对症治疗后好转,其中2例患者死亡。结论:药物诱发高钾血症具有潜在的危险性,需提高警惕,重视防治。
OBJECTIVE： To investigate the characteristics and related factors of drug-induced hyperkalemia, present preven- tive measures and provide reference for the rational drug use. METHODS： 46 literatures of individual cases and group cases of drug-induced hyperkalemia publicly reported in domestic medical journals from 1979 to 2014 were collected and analyzed statistical- ly, including 66 cases. RESULTS： 66 cases with drug-induced hyperkalemia were mainly involved in cardiovascular drugs and im- munosuppressants. Most of them were improved after drug withdrawal and symptomatic treatment, and 2 cases died. CONCLU- SIONS： Drug-induced hyperkalemia are potentially dangerous. It is necessary to be vigilant, prevent and control timely and reduce the incidence of severe adverse reactions.
出处
《中国药房》
CAS
北大核心
2015年第20期2790-2792,共3页
China Pharmacy
关键词
高钾血症
不良反应
安全用药
Hyperkalemia
Adverse reaction
Drug safety
