摘要
糖尿病肾病(DN)是糖尿病中晚期并发症之一,是糖尿病晚期重要的微血管病变,高血压既是其重要的并发症,也是导致肾功能进一步损害和心脑血管病发生的独立危险因素。该类患者临床降压药物合理选用有助于其有效控制血压,减少心脑血管病的发生,并可延缓肾病进程。该文对糖尿病肾病的发病机制、病理生理和血压目标水平进行了简要回顾,重点介绍了DN患者常用降压药物以及联合用药的选择,指导临床该类患者的血压控制。
Diabetic nephropathy （DN） is one of the late complications of diabetes, a major microvascular disease in late diabetic disease, and hypertension is both an important complication and an independent risk factor leading to further damage of kidney function and cardiovascular and cerebrovascular disease. The rational use of antihypertensive drugs on this kind of patients helps control blood pressure effectively, reduce the occurrence of cardiovascular and cerebmvascular diseases,and can delay the disease progress. The pathogenesis of diabetic nephropathy, pathology and blood pressure levels is briefly reviewed,focusing on the introduction of common antihypertensive drugs and combined medication options for DN patients used,to guide the blood pressure control in clinical.
出处
《医学综述》
2014年第9期1621-1624,共4页
Medical Recapitulate
关键词
糖尿病肾病
血压目标水平
降压药物
合理选用
Diabetic nephropathy
Blood pressure target levels
Antihypertensive drugs
Reasonable choice
