摘要
研究表明，成纤维细胞生长因子21（FGF21）可以改善胰岛素抵抗、增加胰岛素敏感性。其通过保护胰岛B细胞、与胰岛素协同、增强线粒体氧化、促进脂联素分泌等发挥作用。脑室内给予FGF21也可改善胰岛素敏感性。FGF21为治疗2型糖尿病、肥胖等疾病带来了新方向。
Studies show that fibroblast growth factor 21 （FGF21 ） plays an important role in improving insulin resistance and increasing insulin sensitivity. FGF21 can protect islet 13 cells, synergize with insulin, enhance mitochondrial oxidation and promote the secretion of adiponectin. Intracere-broventricular infusion of FGF21 can also improve insulin sensitivity. FGF21 provides a new way for the treatment of type 2 diabetes, obesity and so on.
出处
《国际内分泌代谢杂志》
2015年第4期268-270,共3页
International Journal of Endocrinology and Metabolism
