摘要
目的:分析Bi PAP无创通气在中重度慢阻肺稳定期患者临床治疗中的应用效果,探讨Bi PAP通气在临床的应用优势。方法:将本院接诊的148例处于稳定期的中重度慢阻肺患者采用随机数字表法分为两组,对照组73例给予鼻导管吸氧治疗,观察组75例采用Bi PAP通气治疗,比较两组患者运动耐力及肺功能各项指标状况。结果:两组治疗前6 min步行距离、Tmax、Wmax、MVV、FEV1%、RV及FEV1/FVC比较差异均无统计学意义(P>0.05),治疗后观察组以上各项指标均优于对照组(P<0.05);观察组患者的治疗成功率显著高于对照组(P<0.05),死亡率显著低于对照组(P<0.05);两组患者的不良反应发生率比较差异无统计学意义(P>0.05)。结论:给予中重度慢阻肺稳定期患者Bi PAP通气治疗,可有效改善患者运动能力与肺功能,提高患者临床治疗生存率,降低患者死亡率,该法值得临床推广使用。
Objective：To analyze the effect of Bi PAP non-invasive ventilation used in the treatment of moderately severe COPD patients of stable stage and explore its clinical application advantages.Method：148 cases of moderately severe COPD patients in stable stage were randomly divided into two groups.73 cases of the control group were treated with nasal catheter oxygen therapy,75 cases of the observation group were given Bi PAP ventilation therapy.The indexes of exercise endurance and pulmonary function status were compared between the two groups.Result：Before treatment,there were no significant differences between the two groups in the aspects of 6 min walking distance,Tmax,Wmax,MVV,FEV1%,RV and FEV1/FVC（P〈0. 05）.The observation group were significantly better than the control group in the aspects above after the treatment（P〈0. 05）.The success rate of the observation group was significantly higher than that of the control group（P〈0. 05）.The mortality of the observation group was significantly lower than that of the control group（P〈0. 05）.The occurrence of adverse reactions of the two groups had no significant difference（P〉0. 05）.Conclusion：Giving Bi PAP ventilation therapy to the moderately severe COPD patients in stable phase can effectively improve their exercise capacity,pulmonary function and survival rate,it can also reduce their mortality.This method is worth clinical spreading.
出处
《中国医学创新》
CAS
2015年第19期60-62,共3页
Medical Innovation of China
关键词
BI
PAP
慢阻肺
运动耐力
肺功能
Bi PAP
Chronic obstructive pulmonary disease
Exercise tolerance
Pulmonary function
