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刺激状态血清Tg在分化型甲状腺癌的预测意义 被引量:2

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摘要 目的探讨131I治疗前刺激状态甲状腺球蛋白(Tg)在分化型甲状腺癌(DTC)患者中复发和转移的临床价值。方法回顾性分析分化型甲状腺癌接受甲状腺全切/次全切术后患者135例,用131I清除残余甲状腺组织及转移灶前检测血清№并行131I全身扫描(131I-WBS),按照血清TgTg平≤2μg/L、2—10μg/L和≥10μg/L分为3组。结果135N甲状腺癌患者中,56例血清Tg≤2μg/L(4例131I—WBS阳性)、44例血清Tg在2-10μg/L(54例131I-WBS阳性),35例血清Tg≥10μg/L(28例131I-WBS阳性);经病理证实淋巴结转移17例,其中13例血清Tg≥10I.zg/L,血清Tg≤2μg/L和2—10μg/L各2例;肺转移3例,Tg均〉10μg/L。结论刺激状态血清Tg在分化型甲状腺癌术后的监测复发和转移中有重要的临床价值,但应结合131I—WBS、颈部B超等检查作出准确判断。
出处 《浙江临床医学》 2015年第7期1202-1203,共2页 Zhejiang Clinical Medical Journal
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参考文献8

  • 1王治国,张文文,郝珊瑚,张彤,张国旭.血清Tg检测联合^(131)I-WBS在DTC术后的临床价值[J].标记免疫分析与临床,2014,21(1):22-25. 被引量:3
  • 2Zekiye Hasbek, Bulent Turgut, Fatih Kilicli, et al. Importance of Postoperative Stimulated Thyroglobulin Level at the Time of 131I Ablation Therapy for Differentiated Thyroid Cancer. Asian Pacific Journal of Cancer Prevention,2014, 15(6):2523-2527. 被引量:1
  • 3Webb RC, Howard RS, Stojadinovic A, et al. The utility of serum thyroglobuhn measurement at the time of remnant ablation for predicting disease-free status in patients with differentiated thyroid cancer: a meta-analysis involving 3947 patients. J Clin Endocrinol Metab,2012, 97(8):2754-2763. 被引量:1
  • 4Lin Y, Li T, Liang J, et al. Predictive Value of Preablation Stimulated Thyroglobulin and Thyroglobulin/Thyroid-Stimulating Hormone Ratio in Differentiated Thyroid Cancer. Clinical Nuclear Medicine,2011, 36(12):1102-1105. 被引量:1
  • 5Nascimento C, Borget I, A1 Ghuzlan A, et al. Persistent disease and recurrence in differentiated thyroid cancer patients with undetectable postoperative stimulated thyroglobulin level. Endocr Relat Cancer,2011, 18(2):29-40. 被引量:1
  • 6David A, Blotta A, IKossi R, et al. Clinical value of different responses of serum thyroglobulin to recombinant human thyrotropin in the follow- up of patients with differentiated thyroid carcin0ma.Thyroid,2005, 15 (3) :267-273. 被引量:1
  • 7邵喜艳,弓健,郭斌,唐勇进,徐浩.血清Tg和^(131)I-WBS在分化型甲状腺癌^(131)I清除甲状腺后的随访价值[J].广东医学,2011,32(4):481-483. 被引量:5
  • 8Leenhardt L, Erdogan MF, Hegedus L, et al. Europan Thyroid Association Guidelines for cervical ultrasound scan and ultrasound-guide techniques in the postoperative mangement of patients with thyroid cancer. Eur Thyroid J, 2013, 2(3): 147N159. 被引量:1

二级参考文献31

  • 1潘明志,田蓉.Tg阳性与诊断剂量^(131)I-WBS阴性甲癌患者的处理策略研究[J].华西医学,2005,20(2):337-337. 被引量:7
  • 2吴伟宏,朱火根.甲状腺癌误诊及再手术的探讨[J].肿瘤,2006,26(4):385-386. 被引量:5
  • 3戴庆靖,匡安仁.甲状腺球蛋白测定的临床意义及影响因素[J].同位素,2007,20(2):120-124. 被引量:21
  • 4COOPER D S,DOHERTY G M,HAUGEN B R,et al.Management guidelines for patients with thyroid nodules and differentiated thyroid cancer[J].Thyroid,2006,16(2):109-142. 被引量:1
  • 5CHAO M.Management of differentiated thyroid cancer with rising thyroglobulin and negative diagnostic radioiodine whole body scan[J].Clin Oncol 2010,22(6):438-447. 被引量:1
  • 6BAUDIN E,DO CAO C,CAILLEUX A F,et al.Positive predictive value of serum thyroglobulin levels,measured during the first year of follow-up after thyroid hormone withdrawal,in thyroid cancer patients[J].J Clin Endocrinol Metab,2003,88(3):1107-1111. 被引量:1
  • 7SCHAAP J,EUSTATIA RUTTEN C F,STOKKEL M,et al.Does radioiodine therapy have disadvantageous effects in non-iodine accumulating differentiated thyroid carcinoma?[J].Clin Endocrinol,2002,57(1):117-124. 被引量:1
  • 8李少林.核医学[M].5版.北京:人民卫生出版社,2002:352-356. 被引量:4
  • 9BIO F,BAGHINO G,ATZENI F,et al.The diagnostic value for differentiated thyroid carcinoma metastases of thyroglobulin (Tg) measurement in washout fluid from fine-needle aspiration biopsy of neck lymph nodes is maintained in the presence of circulating anti-Tg antibodies[J].J Clin Endocrinol Metab,2006,91(4):1364-1369. 被引量:1
  • 10BACHELOT A,CAILLEUX A F,KLAIN M,et al.Relationship between tumor burden and serum thyroglobulin level in patients with papillary and follicular thyroid carcinoma[J].Thyroid,2002 12(8):707-711. 被引量:1

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