摘要
目的：研究入院肌酐水平在预测慢性心力衰竭患者进行性肾功能损害中的作用。方法：采用病例对照研究方法，分析2组之间入院肌酐水平的差异及肾功能损害发生的独立危险因素，应用ROC曲线得到预测肾功能损害的肌酐临界值。结果：入院肌酐水平在2组之间存在显著差异（P＜0．05），入院肌酐水平与肾功能损害的发生独立相关，OR值为2．248。预测肾功能损害发生的最佳肌酐临界值为112．85umol／L，灵敏度及特异度分别为0．638、0．592。结论：发生肾功能损害者入院肌酐水平明显高于对照组，入院肌酐水平可预测肾功能损害的发生。
Objective：To describe the prediction of creatinine level at admission for worsening renal function（ WRF） in patients with＆nbsp;chronic heart failure.Methods：Data was collected in a nested case-control study on 211 subjects who were hospitalized with HF （66 patients with WRF, de？ ned as a rise in serum creatinine level≥26.5umol/L[0.3mg/dL], and 145 control subjects ）.Compared the differentiation of creatinine level at admission between the two groups, and multivariable analysis was used to identify independent predic-tors for WRF.Get the best critical value of creatinine using ROC curve.Results： Creatinine level at admission was higher in the case group （P〈0.05）.Creatinine level at admission was a independent predictor for WRF （OR=2.248,95%CI：1.088~4.647）.The best critical value of creatinine was 112.85umol/L, sensitivity：0.638, specificity：0.592. Conclusion： Creatinine level at admission was higher in the case group.Creatinine level at admission could predict the occurrence of WRF.
出处
《中国伤残医学》
2015年第14期13-15,共3页
Chinese Journal of Trauma and Disability Medicine
关键词
心力衰竭
肾功能损害
入院肌酐水平
Heart failure
Worsening renal function
Creatinine level at admission
