摘要
目的对妊娠期阴道分泌物检查存在假丝酵母菌而无临床症状的妇女应用乳杆菌阴道胶囊,探讨乳杆菌阴道胶囊对于预防妊娠期外阴阴道假丝酵母菌病发病的效果。方法选择在我院产科门诊就诊单纯阴道分泌物检查假丝酵母菌阳性的孕妇80例,随机分为治疗组和对照组,每组40例。治疗组使用阴道用乳杆菌胶囊,对照组是不做任何用药的空白对照。观察用药3周后治疗组阴道乳杆菌数量及Ig E浓度变化,用药2月后两组的外阴阴道假丝酵母菌病的发病率。结果用药3周后,治疗组阴道乳杆菌数量高于治疗前,阴道Ig E浓度明显低于治疗前(P<0.05)。用药2月后,治疗组发病率为12.5%低于对照组的32.5%(P<0.05)。结论乳杆菌阴道胶囊有助于降低妊娠期外阴阴道假丝酵母菌病的发病率,改善假丝酵母菌所致的阴道微生态失调。
Objective To explore the efficacy of lactobacillus vaginal capsules in V VC iniectlon dulang gestation period. Methods 80 pregnant women in our hospital who were infected VVC were randomly divided into treatment group and control group, each group has 40 pregnants . The patients in treatment group were given lactobacillus vaginal capsules and the other group was blank control. The VVC morbidity, number of lactobacillus in vagina and the changes of IgE concentration were compared between the two groups after three weeks and two months. Results After three weeks treatment, the IgE concentration in vagina of treat- ment group was obviously lower than before treatment （ P〈0.05 ） and the number of lactobacillus in vagina was higher than before treatment. The VVC morbidity in treatment group （ 12.5%） was significantly lower than that in control group （ 32.5% ） after two months of treatmentl P〈0.05 ）. Conclusion Lactobacillus va- ginal capsules can contribute to reduce the VVC morbidity during gestation period and improve the vaginal micro-ecology imbalance caused by VVC infection.
出处
《湘南学院学报（医学版）》
2015年第2期23-25,共3页
Journal of Xiangnan University（Medical Sciences）
基金
深圳市科创委基金项目(200803265)
深圳市南山区科技创新局基金资助项目(2012052)
关键词
妊娠
外阴阴道假丝酵母病
乳杆菌胶囊
pregnancy, vulva vagina candida disease, lactobacillus capsule
