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乳杆菌制剂和(或)达克宁治疗外阴阴道假丝酵母菌病的疗效比较 被引量:12

Preliminary study of curative effect of lactobacillus and(or) antifungal drugs in women with vulvovaginal candidiasis
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摘要 目的 探讨乳杆菌制剂治疗外阴阴道假丝酵母菌病(VVC)的疗效。方法 将2006年5月至7月在温州医学院附属二院确诊为VVC的患者分为3组,单纯使用达克宁栓者(A组)40例,联合使用达克宁栓及定君生阴道栓者(B组)加例,单纯使用定君生者40例(C组),进行对照。对3组的临床症状及真菌学检查结果进行分析讨论。结果 停药3~5d时,A、B组患者的疗效差异无显著性(P〉0.05),C组患者的疗效明显低于A、B两组(P〈0.05);停药30~37d时,A、C组患者的疗效差异无显著性(P〉0.05),B组患者的疗效明显高于A、C两组(P〈0.05)。结论 在应用阴道用乳杆菌治疗VVC时,应首先应用抗真菌药物,当真菌感染得以控制之后再使用乳杆菌,帮助恢复阴道内菌群环境。 Objective To study the effect of lactobacillus(Ding-Jun-Sheng) and (or) antifungal drugs on vulvovaginal candidiasis(VVC). Methods The patients were treated by antifungal drugs (group A), antifungal drugs combined with lactobacillus (group B) and lactobacillus alone (group C). Results 3 -5 d after treatment, no significant difference of the treatment effect was found between group A and B (P 〉 0.05 ), both of which were better than group C (P 〈 0.05 ), and 30~37 d after treatment, group B were better than group A and C (P 〈 0.05 ). Conclusions In the treatment of VVC, the antiftmgal drugs should be used firstly, and lactobacillus can be used to improve the microorganism environment after the infection is controlled.
出处 《中国微生态学杂志》 CAS CSCD 2007年第5期442-443,共2页 Chinese Journal of Microecology
关键词 乳杆菌 外阴阴道假丝酵母菌病 Lactobacillus Vulvovaginal candidiasis
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