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孕宫1号联合甲氨蝶呤、米非司酮保守治疗异位妊娠的有效性与安全性研究 被引量:2

Study on the efficacy and safety of pregnant house No.1 combined with methotrexate,mifepristone in conservative treatment of ectopic pregnancy
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摘要 目的:探讨孕宫1号联合西药保守治疗异位妊娠的有效性与安全性。方法:选择61例异位妊娠患者为研究对象,采用随机数字表法分为对照组(30例)和观察组(31例),对照组采用甲氨蝶呤(MTX)肌注+米非司酮口服治疗,观察组在上述基础上联合中药方剂孕宫1号,比较两组治疗有效性与安全性。结果:观察组治愈率(90.32%)明显高于对照组(P<0.05);阴道流血、腹痛、包块消失、血β-h GG转阴、住院时间、不良反应发生率均明显低于对照组(P<0.05)。结论:孕宫1号辅助西药保守治疗可有效缓解患者临床症状,提高治疗效果,降低不良反应发生率。 Objective: To explore the efficacy and safety of pregnant house No. 1 combined with western medicine in conservative treatment of ectopic pregnancy. Methods: Sixty- one patients with ectopic pregnancy were divided into control group( 30 patients) and observation group( 31 patients) according to random number table; the patients in control group were treated with intramuscular injection of methotrexate and oral administration of mifepristone; while the patients in observation group were treated with intramuscular injection of methotrexate,oral administration of mifepristone,and pregnant house No. 1; the efficacies and safeties in the two groups were compared. Results: The cure rate in observation group was 90. 32%,which was statistically significantly higher than that in control group( P〈0. 05);the incidence rates of vaginal bleeding and abdominal pain,lumps disappear,conversion rate of blood β- human chorionic gonadotropin( β- HGG),hospitalization time,and the incidence rate of adverse reactions in observation group were statistically significantly lower than those in control group( P〈0. 05). Conclusion: Pregnant house No. 1 combined with western medicine can effectively relieve clinical symptoms,improve treatment effect,reduce the incidence rate of adverse reactions.
出处 《中国妇幼保健》 CAS 2015年第18期3012-3014,共3页 Maternal and Child Health Care of China
关键词 异位妊娠 安全性 孕宫1号 保守治疗 Ectopic pregnancy Safety Pregnant house No.1
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