摘要
目的探索米非司酮与甲氨蝶呤对异位妊娠保守治疗的有效率。方法选取2017年4月-2018年4月期间该院异位妊娠100例患者(实施奇偶数法分组模式),对照组的50例患者进行米非司酮治疗,观察组的50例患者进行米非司酮联合甲氨蝶呤治疗。结果观察组包块消失时间(20.43±2.43)d、血β-HCG恢复正常时间(16.78±1.38)d、包块直径(0.27±0.05)mm、总有效率(96.00%)、不良反应发生率(4.00%)、β-HCG水平(1 063.75±54.12)IU/L均优于对照组(t=6.854 4、5.758 4、1.585 6、χ^2=8.745 2、11.232 6、t=482.623 5;P<0.05)。结论对异位妊娠患者实施米非司酮联合甲氨蝶呤保守治疗效果显著,可提高治疗有效率。
Objective To explore the efficient of mifepristone and methotrexate in conservative treatment of ectopic pregnancy. Methods A total of 100 cases of ectopic pregnancy in our hospital from April 2017 to April 2018 were selected. Fifty cases in the control group were treated with mifepristone, and 50 cases in the observation group were treated with mifepristone combined with methotrexate. Results Disappearance time(20.43±2.43)d, blood β-HCG recovery time(16.78±1.38)d, mass diameter(0.27±0.05) mm, total effective rate(96.00%), incidence of adverse reactions(4.00%),β-HCG level(1 063.75±54.12) IU/L in the observation group were better than those in the control group(t=6.854 4, 5.758 4, 1.585 6,χ^2=8.745 2, 11.232 6, t=482.623 5;P<0.05). Conclusion Mifepristone combined with methotrexate is effective in the treatment of ectopic pregnancy.
作者
肖伟伟
XIAO Wei-wei(Department of Obstetrics and Gynecology,Xiajin County People's Hospital,Dezhou,Shandong Province,253200 China)
出处
《系统医学》
2019年第9期130-132,共3页
Systems Medicine
关键词
米非司酮
甲氨蝶呤
异位妊娠
保守治疗
有效率
Mifepristone
Methotrexate
Ectopic pregnancy
Conservative treatment
Efficient
