摘要
目的:探讨采用NCPAP治疗早产儿呼吸窘迫综合征的综合疗效及对患儿血气指标和肺部感染率的影响。方法:选取自2012年1月至2014年1月我院妇产科出生且出生后30min即转入新生儿科住院的早产儿48例,按照登记序列号分组,单号为对照组24例,双号为观察组24例。对照组采用NCPAP,观察组采用NCPAP联合PS,观察两组患儿的疗效及血气指标、肺部感染率的变化。结果:观察组总有效率95.83%显著高于对照组的75.00%(χ2=4.181,P=0.041);观察组VAP发生率83.33%明显低于对照组的33.33%(χ2=4.547,P=0.033);两组患儿用药后1、6h血气指标均较用药前明显改善(P<0.05),观察组用药后1、6h血气指标均较对照组改善显著(P<0.05)。结论:NCPAP联合PS治疗NRDS可显著提高疗效,改善血气指标,降低肺部感染率。
Objective：To investigate the comprehensive efficacy and effects on blood gas and lung in-fection rates of NCPAP in treatment of respiratory distress syndrome in preterm children.Method：48 cases the birth and 30 minutes after birth of premature children was transferred to the neonatal hospitalization were selected from obstetrics and gynecology department in our hospital from January 2012 to January 2014, grouping according to the serial number registration, 24 cases of the single number as the control group, 24 cases of the double number as the observation group.The control group were given NCPAP, the observation group were given NCPAP joint PS, efficacy and blood indicators ,changes in the lung infection of two groups were compared.Result：Total efficiency of the observation group was 95.83%,which was significantly higher than the 75.00%in control group（χ2=4.181,P=0.041）;VAP incidence of the observation group was 83. 33%significantly higher than the 33.33%in control group（χ2=4.547,P=0.033）;The index of blood gas 1 hour,6 hours, after treatment of two groups were significantly improved than before treatment （ P〈0.05 ） , blood gas 1 hour, 6hours after treatment of the observation group were significantly improved than the control group（P〈0.05）.Conclusion：NCPAP combined with PS in treatment of NRDS can significantly improve the efficacy, improve blood indicators, reduce lung infection.
出处
《河北医学》
CAS
2015年第9期1426-1429,共4页
Hebei Medicine
基金
中国高校医学期刊临床专项资金项目
(编号:11321201)
关键词
早产儿呼吸窘迫综合征
疗效
NCPAP
NCPAP
Respiratory distress syndrome in preterm children
Efficacy
