摘要
目的探讨丙种蛋白静脉注射（IVIG）治疗新生儿重症肺炎的临床疗效。方法将95例新生儿重症肺炎患儿随机分为IVIG治疗组和常规治疗组，常规组45例给予抗生素、给氧、血管活性药物，保暖及支持疗法，部分患儿输过1—2次血浆；IVIG组50例给予常规治疗＋IVIG。结果使用IVIG后血清IgG水平提高59．46％，而IgA、IgM无明显改变，补体C3水平明显降低，T4^＋细胞和T4／T8比例降低，但差异未见统计学意义（P〉0．05）。结论IVIG在改善症状、消除肺部体征、缩短住院时间和提高治愈率等方面均优于常规治疗。
Objective To investigate the clinical effect of intravenous injection of gamma globu- fin（IVIG） on infants with severe pneumonia. Methods Ninety-five neonatal severe pneumonia patients were randomly divided into IVIG treatment group and routine treatment group, the 45 patients in routine treatment group were given antibiotics, oxygen, vasoactive drugs, warmth and support therapy, some pa- tients had 1 to 2 times infusion of plasma; the 50 patients in IVIG group were given routine treatment ＋ IVIG. Results The level of serum IgE improved by 59. 46% after using IVIE, and IgA, IgM had no obvi- ous change, complement C3 levels decreased significantly, T4 ^＋ cells and the T4/T8 ratio decreased, but there was no significant difference. Conclusions IVIG is superior to routine treatment in improving symp- toms, eliminate the physical signs of the lungs, shorten hospitalization time and improve the cure rate.
出处
《中国实用医刊》
2015年第13期23-24,共2页
Chinese Journal of Practical Medicine
关键词
静脉滴注
丙种球蛋白
新生儿
重症肺炎
Intravenous infusion
Gamma globulin
Newborn
Severe pneumonia
