摘要
目的评价疏筋壮骨汤治疗绝经后骨质疏松症的疗效。方法将80例患者按照随机数字表法随机分为治疗组和对照组,各40例,治疗组予疏筋壮骨汤(葛根、熟地黄、当归、白芍等),对照组予仙灵骨葆胶囊,连续6个月,监测2组治疗前后骨密度、血清骨转化指标。结果 2组骨密度均有不同程度上升,治疗前后比较差异具有统计学意义(P<0.05);治疗组血清中骨钙素(OC/BGP)、降钙素(CT)、雌二醇(E2)水平上升,抗酒石酸酸性磷酸酶(TRAP)水平下降,与治疗前比较差异有统计学意义(P<0.05)。结论应用疏筋壮骨汤治疗绝经后骨质疏松症,能升高血清骨密度,使血清中骨钙素、降钙素、雌二醇水平上升,抗酒石酸酸性磷酸酶水平下降。
Objective Evaluation of Shujinzhuanggu decoctions therapy in postmenopausal osteoporosis. Methods The 80 patients in accordance with the method of random number table were randomly divided into treatment group and control group 40 cases, the treatment group was given Shujinzhuanggu decoctions （Pueraria, Rehmannia, Angelica, White peony root etc. ）, the control group were given Xianlinggubao capsule, consecutive six-month monitoring bone mineral density before and after treatment, serum bone turnover indicators. Results Two groups of patients after treatment increased bone mineral den- sity in varying degrees, before and after treatment difference was statistically significant （P 〈 0.05） ; Shujinzhuanggu decoc- tion group of patients after treatment serum osteocalcin （OC/BGP）, drop calcium （CT）, estradiol （E2） levels rise, tartrate- resistant acid phosphatase （TRAP） levels decreased, compared with before treatment difference was statistically significant （P 〈 0.05）. Conclusion Applications of Zhuanggu decoction treatment of postmenopausal osteoporosis, efficacy and side effects.
出处
《长春中医药大学学报》
2015年第3期585-586,共2页
Journal of Changchun University of Chinese Medicine
基金
吉林省科技发展计划项目(20130206064YY)
关键词
骨质疏松症
绝经
疏筋壮骨汤
osteoporosis
postmenopausal
Shujinzhuanggu decoction
