摘要
目的探讨湿热蕴结型大肠癌(CRC)术后患者的舌象变化与中医症候之间的相关性。方法将100例湿热蕴结型CRC术后患者随机分为2组,治疗组72例应用肠益方加减治疗,对照组28例应用平消胶囊治疗。2组均治疗3个月。采用ZBOX-Ⅰ型中医舌脉象数字化采集分析系统采集患者治疗前后的舌象参数,并由计算机软件对舌象参数进行自动分析;同时对患者治疗前后中医症候进行评分;观察治疗前后患者舌象参数与中医症候的变化,并用统计学软件分析舌象参数与中医症候之间的相关性。结果 2组治疗前后舌象苔质参数变化比较差异无统计学意义(P>0.05)。治疗组湿热夹瘀证治疗后胖瘦指数较本组治疗前升高(P<0.05),胖瘦指数由治疗前的瘦舌转变为治疗后的正常舌;对照组治疗后齿痕指数较本组治疗前降低(P<0.05)。2组治疗前后中医症候总评分比较差异均有统计学意义(P<0.05),治疗后降低。治疗组湿热兼虚证治疗后总有效率高于对照组(P<0.05)。治疗组治疗后中医单项症候评分均较本组治疗前降低(P<0.05);对照组治疗后黏液便、肛门灼热、口苦、神疲乏力、面色萎黄这5项中医症候评分较本组治疗前降低(P<0.05)。治疗组湿热夹瘀证治疗后面色萎黄这1项中医症候疗效优于对照组(P<0.05);治疗组湿热兼虚证治疗后腹部疼痛、腹痛固定、面色萎黄这3项中医症候疗效优于对照组(P<0.05)。2组患者治疗前后的舌象参数及中医单项症候评分进行Pearson简单相关系数的相关性分析,舌象胖瘦指数与黏液便的相关系数最大为-0.162,且呈负相关(P<0.05)。结论肠益方能改善湿热夹瘀证CRC术后患者舌象的胖瘦程度;改善湿热蕴结型CRC术后患者的中医症候,且疗效优于对照组;湿热蕴结型CRC术后患者舌象参数与中医症候具有一定的相关性。
Objective To observe the correlation of tongue parameters in postoperative colorectal cancer pa-tients with damp-heat accumulation type and traditional Chinese medicine （ TCM） syndrome.Methods 100 post-operative colorectal cancer patients with damp -heat accumulation type were randomly divided into two groups .72 pa-tients in treatment group were treated by Changyi herbs ,28 patients in control group were treated by Pingxiao capsule . The course was three months in two groups .The tongue parameters of patients were collected by type ZBOX -I digital collection and analysis system of tongue and pulse manifestation before and after treatment ,and received computer au-tomatic analysis.The scores of TCM syndrome were recorded in two groups .The changes of tongue parameters and TCM syndrome were observed before and after treatment ,and the correlation between tongue parameters and TCM syn-drome were analyzed by statistical software .Results There was no statistical significance between two groups on the tongue parameters before and after treatment （ P 〈0.05）.The fat index of damp -heat accumulation type after treatment was increased in treatment group （ P〈0.05）,the tongue turn thin tongue before treatment into normal tongue after treatment .The teeth prints after treatment was decreased in control group （P〈0.05）. There was statistical significance before and after treat-ment on TCM syndrome score in two groups （P〈0.05）,and the score after treatment was decreased .The total effec-tive rate of damp-heat accumulation type in treatment group was higher than that in control group （P〈0.05）.The single syndrome score of TCM after treatment were decreased in treatment group （P〈0.05）.The TCM syndrome score of mucous stool,burning pain in anus,bitter taste,weariness and sallow complexion after treatment were de-creased in control group （P〈0.05）.The improvements of sallow complexion of damp -heat accumulation type in treatment group after treatment was superior to that in control group
出处
《河北中医》
2015年第5期660-665,共6页
Hebei Journal of Traditional Chinese Medicine
基金
上海市教育委员会市属高校上海市重点学科(第三期)(编号:S30302)
关键词
结直肠肿瘤
辨证分型
中医病机
舌质
症候
Colorectal neoplasms
Syndrome differentiation
Chinese medical pathogenesis
Tongue nature
Syndrome
