摘要
目的:系统评价补阳还五汤治疗出血性中风急性期的临床疗效及安全性。方法 :运用系统评价方法 ,检索补阳还五汤治疗中风的随机对照试验文献,筛选合格研究,评价研究质量,采用异质性检验、Meta-分析、敏感性分析、倒漏斗图等方法统计相关数据。结果:4项研究符合选择标准,补阳还五汤治疗出血性中风急性期总有效率的RR(99%CI)、神经功能缺损评分及血肿吸收情况的WMD(99%CI)统计结果依次为1.15(0.88,1.51)、-6.73(-13.71,0.25)、-1.42(-7.51,4.67)。结论:目前尚无充分证据支持补阳还五汤有益于改善出血性中风急性期神经功能缺损状况、日常生活活动能力及颅内血肿吸收情况。
Objective：To systematically evaluate the efficacy and safety of Buyang Huanwu decoction for treatment of hemorrhagic stroke of acute phase. Methods：With the method of system evaluation,randomized controlled trails （RCTs） of Buyang Huanwu decoction for treatment of hemorrhagic stroke of acute phase were retrieved,the eligible studies were included and the quality of the inclusive trails was assessed. The related data was analyzed by heterogeneity test,meta-analysis,sensitivity analysis and inverted funnel plot. Results：4 RCTs were included. The recta-analysis indicated that the relative risk（RR） of overall effective rate was 1.15[99%CI],the WMD（99%CI） of neural function defect score was -6.73（-13.71,0.25） and the WMD （99%CI） of absorption of hematoma was -1.42（-7.51,4.67）. Conclusion：At present,the evidence for im- provement of neural function defect,activities of daily living and absorption of intracranial hematoma of hemorrhagic stroke of acute phase by Buyang Huanwu decoction is insufficient.
出处
《山东中医药大学学报》
2015年第3期203-204,共2页
Journal of Shandong University of Traditional Chinese Medicine
基金
国家自然基金委资助课题(编号:30801458)
关键词
补阳还五汤
出血性中风急性期
系统评价
随机对照试验
Buyang Huanwu decoction
hemorrhagic stroke of acute phase
systematic review
randomized controlled trail
