摘要
目的:探讨速度向量成像(VVI)技术检测慢性肾脏疾病(CKD)早期患者左心室舒缩功能早期变化的价值。方法:选取30例左心室正常构型CKD早期患者(A组)和30例向心性重构CKD早期患者(B组),以30名健康体检者为对照(C组)。常规超声测定左心室舒张末期内径(LVIDd)、室间隔厚径(IVST)、左心室后壁厚径(LVPWT)、左心室射血分数(LVEF)、二尖瓣口舒张期血流频谱E、A比值;VVI技术测定左心室长轴16节段收缩期峰值应变率(SSRMAX)、舒张早期、晚期峰值应变率(DSRMAX/e、DSRMAX/n),进行各组之间的参数比较。结果:3组间LVEF差异无统计学意义。B组的E/A值低于C组及A组(均P<0.05)。B组部分局部心肌节段SSRMAX及舒张早期DSRMAX/e低于A组和C组(均P<0.05);A组舒张早期部分局部心肌节段DSRMAX/e低于C组(P<0.05),而A、C两组SSRMAX各个节段心肌间无明显差异;3组间各节段心肌舒张晚期DSRMAX/n无统计学差异。结论:VVI技术可以定量评价左心室局部功能,尽早发现CKD早期患者节段心肌舒缩功能变化。
Objective：To evaluate the early changes of left ventricular systolic and diastolic function in patients with early chronic kidney disease （CKD） using velocity vector imaging （VVI） technique. Metbod.Thirty cases of early CKD patients with normal configuration （group A）, 30 cases of early CKD patients with concentric remode- ling （group B）, and 30 cases of healthy subjects as control group （group C） were selected in this study. The left ventricular internal dimension in diastole （LVIDd）, interventricular sepal thickness （IVST）, left ventricular posterior wall thickness （LVPWT）, left ventricular ejection fraction （LVEF）, diastolic mitral flow spectrum E and A ratio （E/A） were determined by conventional echocardiography. The systolic maximum strain rate （SSRMAx） and early and end diastolic maximum strain rate （DSRMAX/e, DSRMAX/e） of left ventrieular long axis 16 segment were determined by VVI, The parameters were compared among the groups. Result： LVEF had no statistical significance among three groups. E/A value in group B was lower than that in group C and group A （both P〈0.05） re gional myocardial SSRMAx and DSRMhx/e in group B were lower than those in group A and group C （all P〈0.05） regional myocardial DSRMAx/e in group A was lower than that in group C, while the SSRMAX of all myocardial seg- ments had no obvious difference between group A and group C. The DSRMAX/n in all myocardial segments showed no significant difference among the three groups. Conclusion..VVI technology can quantitatively evaluate regional left ventricular function,providing the early detecting of segmental myocardial systolic and diastolic function in pa- tients with early CKD.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2015年第5期564-568,共5页
Journal of Clinical Cardiology
关键词
慢性肾脏疾病
超声检查
心室节段心功能
速度向量成像
chronic kidney disease
ultrasonic inspection
ventricular segmental cardiac function
velocityvector imaging
