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体外反射式共聚焦扫描显微镜在结节型基底细胞癌诊断中的应用 被引量:6

Application of the Reflectance Confocal Microscopy in the Diagnosis of Nodule Basal Cell Carcinoma
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摘要 目的观察基底细胞癌的反射式共聚焦扫描显微镜(皮肤CT)影像特征,探讨其在诊断基底细胞癌中的应用价值。方法对在我科就诊的42例临床上初步考虑基底细胞癌的患者,在患者采用皮肤CT检查,后取该处皮损进行组织病理学检查,并将两者作比对,从而对基底细胞癌的皮肤CT影像特征进行归纳总结。结果皮损处皮肤CT的特征:瘤细胞聚集成岛屿状或条索状分布,由密集的异型肿瘤细胞构成,周边细胞呈栅栏状排列。瘤细胞团内可见明亮的高折光性树枝状细胞。与HE染色诊断具有100%的符合率。结论基底细胞癌在皮肤CT成像中具有明显的特点,为无创诊断基底细胞癌提供了新的方法 。 Objective To investigate the image features and further assess application value in the diagnosis of basal cell carcinoma using reflectance confocal microscopy (RCM).Methods 42 patients clinically diagnosed as basal cell carcinoma firstly examined by RCM,and then were taken for histopathologic examination.We summarized the image characteristics of basal cell carcinoma and compared the diagnosis rate by two methods.Results The characteristics of RCM were that dense allotype tumor cell aggregated into island or stripe which neighboring cells were palisading pattern.There was visible bright high refraction of dendritic cells infiltrated into tumor cell clusters.The coincidence rate of diagnosis was 100% compared to haematoxylin and eosin staining.Conclusion RCM have obvious features for basal cell carcinoma,and provides a new method as a noninvasive diagnosis method of basal cell carcinoma.
出处 《中国中西医结合皮肤性病学杂志》 CAS 2015年第2期69-71,共3页 Chinese Journal of Dermatovenereology of Integrated Traditional and Western Medicine
基金 自治区卫生厅青年科技人才专项科研项目(2014Y07)
关键词 共聚焦扫描显微镜 基底细胞癌 影像 Reflectance confocal microscopy Basal cell carcinoma Image features
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