摘要
目的：了解衡阳地区HIV/AIDS患者合并肠道寄生虫感染状况及流行病学特征。方法：随机抽样衡阳地区HIV/AIDS患者开展流行病学调查,并收集其粪便检测肠道寄生虫。结果：152例HIV/AIDS患者的粪便标本中有61例合并肠道寄生虫感染,感染率为40.13%。隐孢子虫、人芽囊原虫、蓝氏贾第鞭毛虫、微孢子虫、阿米巴原虫感染率分别为13.16%、9.87%、9.21%、5.26%、2.63%,五种肠道寄生虫感染率差异有统计学意义（P〈0.05）。城市与农村HIV/AIDS患者肠道寄生虫感染率分别为30.12%和52.17%,差异有统计学意义（P〈0.05）;卫生习惯好坏的HIV/AIDS患者肠道寄生虫感染率分别为33.68%和50.88%,差异有统计学意义（P〈0.05）;HIV感染者和AIDS患者肠道寄生虫感染率分别为25.0%和52.38%,差异有统计学意义（P〈0.05）;不同CD4＋T淋巴细胞计数水平（cells/μl）,HIV/AIDS患者肠道寄生虫感染率有差异,〈200为64.81%,200~499为48.84%,≥500为9.09%,差异有统计学意义（P〈0.05）。结论：HIV/AIDS患者合并肠道寄生虫感染率与寄生虫的种类、卫生习惯、病程、居住环境及CD4＋T淋巴细胞数量有关,而与年龄、性别、受教育程度及经济收入无关;HIV/AIDS患者肠道寄生虫检测应列入常规检测项目。
Objective： To analyze intestinal parasite infection and its epidemiological characteristics in HIV/AIDS patients. Methods： An epidemiological survey was carried out by random sampling of HIV/AIDS patients in Hengyang. The samples of the HIV/AIDS patients＇ stool were collected to detect intestinal parasite. Results： The overall infection rate of intestinal parasite in HIV/AIDS patients was 40. 13%. The infection rates of Cryptosporidium, Blastocystis hominis, Giardia lamblia, microsporidia, Amiba protozoa in HIV/AIDS patients were 13. 16%, 9. 87%, 9. 21%, 5. 26%, 2. 63%. The infection rate of the five types of intestinal parasites in HIV/AIDS patients were significantly different（P〈0. 05 ）. The infection rate of intestinal parasite was 30. 12% in the urban HIV/AIDS patients while it was 52. 17% in the countryside （P〈0. 05 ）. The infection rate of intestinal parasite on health habits, different stages of the disease were also significantly different（P〈O. 05 ）. The infection rates of intestinal parasite with different CIM＋ T cell counts（ 〈200,200-499,3500 cells/ pl） were respectively 64. 81% ,48. 84% ,9.09%. And the difference was significant（P〈 0. 05 ）. Conclusion： The infection rates of intestinal parasite in HIV/AIDS patients was associated with parasite species, health habits, stage of the disease, patients＇ living environment and CD4^＋ T cell count but was not associated with on patients＇ age, gender, their education or economic income. Examination of intestinal parasite should be included among routine examination project for HIV/AIDS patients.
出处
《中国免疫学杂志》
CAS
CSCD
北大核心
2015年第5期695-697,共3页
Chinese Journal of Immunology
基金
湖南省科技计划项目(No.2014FJ3126)
衡阳市科学技术发展计划项目(No.2014KJ27)
湖南省林业科技创新专项资金(No.XLK201432)
衡阳市社会科学基金(No.2014D100)资助
