摘要
目的为进一步提高临床对胰十二指肠切除术后乳糜漏的治疗效果,探讨不同的营养支持方案在术后乳糜漏治疗中的作用。方法选择2009年1月至2014年12月行胰十二指肠切除术并发乳糜漏的36例患者作为研究对象进行回顾性分析,根据患者营养支持方案的不同分为对照组(低脂饮食)和观察组(全肠外营养),每组各18例。观察和比较两组患者各项营养检测指标的变化及恢复情况。结果治疗2周后,观察组患者的血清总蛋白、白蛋白、纤维连接蛋白均明显高于对照组,两组比较差异均有统计学意义(P均<0.05)。观察组患者的恢复指标:乳糜液消失时间、饮食恢复时间、引流管放置时间、住院时间均明显优于对照组,两组比较差异均有统计学意义(P均<0.05)。结论对于胰十二指肠切除术后发生乳糜漏的患者在给予生长抑素等常规药物治疗的同时辅以全肠外营养支持治疗,能较快改善患者营养状况,有利于患者康复。
Objective To investigate the effects of different nutritional support schemes for treating chylous leakage after pancreaticoduodenectomy in order to further improve the clinical therapeutic effect for the treatment of chylous leakage after pancreaticodnodenectomy. Methods Thirty-six patients with chylous leakage after panereaticoduodenectomy who under- went pancreaticoduodenectomy between January 2009 and December 2014 were selected as the research objects to retro- spectively analyze. The patients were divided into two groups （ n = 18 each ） ： low fat diet group （ control group） and total parenteral nutrition group （ observation group） according to the nutritional support scheme. The changes of the detected nu- tritional indicators and the recovery situation in two groups were observed and compared. Results The serum total protein （TP） ,albumin （ALB） and fibroncctin （FN） two weeks after therapy in observation group were significantly higher than those in control group （ all P 〈 0.05 ）. The recovery related indicators including chylous ascites disappearance time, recove- ring oral intake time, drainage tube placement time, hospital stay time in observation group were all significantly better than those in control group （ all P 〈 0.05 ）. Conclusions For the patients with chylous leakage after pancreaticoduodenectomy, on top of somatostatin and other conventional drugs,total parenteral nutrition support therapy may improve patients＇ nutri- tional situation and contribute to the patients＇ rehabilitation.
出处
《中国临床研究》
CAS
2015年第5期556-558,共3页
Chinese Journal of Clinical Research
基金
四川省科技厅支持项目(2011FZ0009)
关键词
乳糜漏
胰十二指肠切除术
肠外营养
低脂饮食
Chyle leakage
Panereaticoduodenectomy
Parenteral nutrition
Low fat diet
