摘要
目的:研究阿司匹林、氯吡格雷双联抗血小板聚集联合阿托伐他汀钙强化降脂治疗伴基底动脉狭窄的后循环梗死的效果。方法:50例伴基底动脉狭窄的后循环梗死患者随机分组,对照组给予抗血小板聚集及常规降脂治疗;观察组给予双联抗血小板聚集及强化降脂治疗。疗程均为3周。在治疗前和治疗后1、2、3周分别进行神经功能缺损程度评分(NIHSS)。结果:观察组的有效率92.0%,观察组对神经功能缺损的治疗效果优于对照组(P<0.01)。两组患者均没有发生严重出血情况及肌肉疼痛情况。结论:短时间应用阿司匹林、氯吡格雷双联抗血小板聚集联合强化降脂对伴基底动脉狭窄的后循环梗死治疗效果优于单独使用阿司匹林及常规降血脂组,且不会发生严重的出血事件。
Objective：To study the curative effect of dual antiplatelet aggregation and intensive lipid lowering on posterior circulation infarction patients with basilar artery stenosis. Method：Fifty posterior circulation infarction patients with basilar artery stenosis were randomly allocated into control group and observation group. Patients in the control group were treated by antiplatelet aggregation and conventional lipid lowering treatment. Observation group was given dual antiplatelet aggregation and intensive lipid lowering treatment. Course of treatment lasted three weeks. National Institutes of Health Stroke Scale（NIHSS）was tested before therapy and after the treatment of 1,2,3 weeks. Result：Efficiency was 92.0%in the observation group,nerve function defect treatment effect of the observation group was better than that of the control group（P〈0.01）. Both of the two groups had no severe hemorrhage and muscular aches. Conclusion：Short time of aspirin,clopidogrel dual antiplatelet aggregation combined with intensive lipid lowering treatment on posterior circulation infarction patients with basilar artery stenosis is better than aspirin alone and conventional lipid lowering group;and no severe hemorrhage happens.
出处
《中国医学创新》
CAS
2015年第13期32-34,共3页
Medical Innovation of China
关键词
双联抗血小板
强化降脂
基底动脉狭窄
后循环梗死
Dual antiplatelet
Intensive lipid lowering
Basilar artery stenosis
Posterior circulation infarction
