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Rspo1通过Wnt/β-catenin信号通路调节成骨细胞分化的研究进展 被引量:3

Research progress of Rspo1 regulation of osteoblast differentiation through the Wnt / β-catenin pathway
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摘要 在成骨细胞的分化增殖中,经典Wnt/β-catenin通路起着重要的调节作用;此通路中的任何一个因子都能影响成骨细胞的分化增殖。近几年里,大量研究证明R-脊椎蛋白家族已成为Wnt/β-catenin信号通路的重要调节因子。本文就Rspo1通过Wnt/β-catenin信号通路调控影响成骨细胞分化增殖的研究进展作一综述。 The classic Wnt/β-catenin pathway plays a crucial role in the differentiation and proliferation of osteoblasts.Any factor in the pathway can affect the proliferation and differentiation of osteoblasts.In recent years, a large number of studies show that R-spondins ( RSPOs) is an important regulating factor in Wnt/β-catenin signaling pathway.This paper reviews the progress in Rspo1 regulation of osteoblast differentiation through Wnt/β-catenin signaling pathway.
出处 《中国骨质疏松杂志》 CAS CSCD 北大核心 2015年第4期504-507,共4页 Chinese Journal of Osteoporosis
关键词 Rspo1 WNT/Β-CATENIN信号通路 成骨细胞 Rspo1 Wnt/β-catenin pathway Osteoblast
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