摘要
目的观察同期经尿道手术治疗浅表性膀胱癌合并前列腺增生的临床疗效。方法选取2009年1月～2012年3月期间本院接受手术治疗的108例浅表性膀胱癌合并前列腺增生患者。采用随机数表法将108例患者分为观察组和对照组，各54例。观察组患者采用经尿道膀胱电切术（TURBt）＋经尿道前列腺切除术（TURP）治疗。对照组患者采用TURBt进行治疗。两组患者术后均给予毗柔比星膀胱内灌注，对比两组患者手术时间、术中出血量、住院时间、术后复发率、残余尿、最大尿流率、尿道狭窄发生率。结果对照组患者的手术时间、术中出血量、住院时间显著少于观察组患者，两组间比较差异具有统计学意义（P〈0．05）。观察组患者的术后复发率、尿道狭窄发生率均低于对照组患者，两组间比较差异具有统计学意义（P〈0．05）。两组患者均未发生前列腺部肿瘤种植，观察组患者较对照组患者术后的最大尿流率显著升高，残余尿减少，两组间比较差异具有统计学意义（P〈0．05）。结论同期经尿道手术治疗浅表性膀胱癌合并前列腺增生具有较好的安全性，能够降低术后膀胱癌的复发率，改善患者的排尿情况和生活质量。
Objectives To investigate the clinical efficacy of trans urethral surgery on superficial bladder cancer combined with benign homeostatic hyperglycemia. Methods To analyzelog cases of superficial bladder cancer combined with benign homeostatic hyperglycemia in our hospital from January 2009 to March 2012. 108 pa- tients were randomly allocated into the observation group or the control group, Patients in observation group were trea- ted with trans urethral resection of the bladder（TURBt） and trans urethral resection of the prostate （TURP） treat- ment. While in the control group with TURBt treatment. All patients have received pirarubiein intravesical instillation postoperatively, Statistics has been used in different data, such as surgery time, blood loss, hospital stay, recurrence rate, residual urine, maximum flow rate, the incidence of urethral stricture etc. Results The operative time, blood loss and hospital stay in control group were significantly less than the observation group （ P 〈 0.05 ）. Mean- while,, recurrence and urethral stricture in the observation group were less than in the control group. Analysis showed a significant difference between these two groups （ P 〈 0.05 ）. No prostate tumors have been found in both two groups. Much more increased maximum urinary flow rate and less decresed residual urine have been confirmed in ob- servation group than in the other, which showed an obvious difference in statistics（ P 〈 0.05 ）. Conclusions It security to perform a trans urethral surgery earlier treatment of superficial bladder cancer combined with benign ho- meostatic hyperglycemia, which can reduce the recurrence rate of bladder cancer, improve urination as well as quality of life. However, advanced research should be done to make certain the inpact of the treatment for one disease to an- other.
出处
《国际泌尿系统杂志》
2015年第3期341-344,共4页
International Journal of Urology and Nephrology
关键词
膀胱肿瘤
前列腺增生
尿道
Urinary Bladder Neoplasms
Prostatic Hyperplasia
Urethra
