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右美托咪定在临床麻醉中的作用优势 被引量:45

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摘要 右美托咪定是一种高选择性α2-肾上腺受体激动剂,其对α2、α1受体的选择性为1 620∶1。右美托咪定激动中枢和外周α2-受体,发挥良好的镇静、镇痛、降低交感活性等作用,无明显呼吸抑制。这些优越的药理作用使右美托咪定于1999年获准用于ICU患者的镇静,2009年被批准用于全身麻醉气管插管及机械通气的镇静。近几年来,右美托咪定作为一种临床麻醉辅助用药已在国内外普遍应用。
作者 赵娟 郑丽宏
出处 《实用医学杂志》 CAS 北大核心 2015年第8期1355-1357,共3页 The Journal of Practical Medicine
基金 黑龙江省自然科学基金资助项目(编号:201039)
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