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针刺联合椎管内麻醉的辅助镇静效果分析 被引量:2

Sedation Effect of Acupuncture Combined with Intrathecal Anesthesia Analysis
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摘要 目的:观察针刺联合椎管内麻醉用于辅助镇静的有效性和安全性。方法:对ASA分级为I级或II级的320例经明确要采用椎管内麻醉的手术患者随机分为实验组和对照组两组,每组分别为160例。实验组患者针刺联合静脉注射咪达唑仑4μg/kg辅助镇静,对照组患者静脉注射咪达唑仑4μg/kg辅助镇静。记录两组给药前(T0),给药后10 min(T1),20 min(T2),30 min(T3)和患者苏醒后(T4)各时点的RR、MAP、HR、SPO2以及OAA/S评分情况,以及手术过程中两组患者出现的不良反应发生率。结果:对照组的患者在T2和T3时间点的RR和SPO2与用药前相比明显降低(P<0.05);实验组和对照组两组研究对照在T3时间点的OAA/S分级评分明显低于用药前的评分(P<0.05)。在手术过程中对照组患者出现呼吸抑制、上呼吸道梗阻和恶心呕吐等不良反应的发生率明显高于实验组(P<0.05)。结论:针刺联合椎管内麻醉采用咪达唑仑比使用依托咪酯具有较好的辅助镇静作用,安全性高,呼吸抑制程度较轻。 Objective : To observe the effect of acupuncture combined spinal epidural anesthesia for efficacy and safety of sedation. Methods : 320 cases of ASA grade I or II level by explicitly rouse spinal anesthesia of operation were randomly divided into experimental group and control group two groups, each group were 160 cases. The patients in the experimental group of acupuncture combined with intravenous midazolam 4ug/kg sedation, patients in the control group with intrave- nous midazolam sedation 4ug/kg. In two groups were recorded before administration (TO) , after administration of 10min ( T1 ) , 20rain (T2) , 30min (T3) and patientsrecovered (T4) at the RR, MAP, HR, SPO2 and OAA / S score, the in- cidence of adverse reactions in two groups of patients as well as in the process of operation. Results : The patients in the control group T2 and T3 time point of RR and SP02 significantly decreased as comparedwith before treatment (P 〈 0. 05 ) ; the study group of two groups in the OAA/S classification T3time point score was significantly lower than that be- fore treatment were the experimental control group and (P 〈 0.05 ). In the process of operation control group patients with upper airway obstruction and respiratory depression, nausea and vomiting and other adverse reactions were significantly higher than that in the experimental group ( P 〈 0. 05 ). Conclusion: Acupuncturecombined spinal epidural anesthesia with midazolam sedation effect is better than the use ofetomidate, high safety, respiratory depression to a lesser degree.
作者 丁一 俞盛辉
出处 《中华中医药学刊》 CAS 北大核心 2015年第5期1275-1277,共3页 Chinese Archives of Traditional Chinese Medicine
关键词 针刺 咪达唑仑 镇静 椎管内麻醉 acupuncture midazolam sedation spinal anesthesia
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