摘要
目的了解目前哈尔滨市引起猩红热及相关疾病的A组链球菌的病原学变化,为该病的防治策略提供参考。方法采集病例的咽拭子标本,送至中国疾病预防控制中心传染病所鉴定及基因测序。结果样品合格率89.9%;共分离培养出18株A族链球菌(GAS);共鉴定出4种EMM型。结论 2011年哈尔滨地区猩红热病原流行的血清型主要为M12型,包含高毒力抗原基因;耐药结果提示菌株对红霉素、克林霉素耐药率达100%,对青霉素等其他5类药物均保持敏感。
Objective To learn about the etiology changes of group A of streptococcus （GAS） of which can cause scarlatina and related diseases in Harbin, and provide reference for the diseases control strategies. Methods Throat swabs specimens were collected and sent to the Infectious Diseases Department of China＇ s CDC for identification and gene sequencing. Results The qualified rate of the samples was 89. 9% ; 18 GAS were separated and cultivated; 4 EMM types were identi- fied. Conclusion The main pathogenic popular serotype of scarlatina is M12 type in Harbin 2011, which includes high virulence antigen gene; Drug resistance results suggest that bacteria strain resistant to erythromycin and clindamycin can reach to 100% and is sensitive to other five drugs besides penicillin.
出处
《中国卫生工程学》
CAS
2015年第2期157-159,共3页
Chinese Journal of Public Health Engineering
基金
哈尔滨市科技局科技创新人才项目(2013RFQQJ058)
