摘要
目的探讨肠球菌属细菌分布及耐药性特征,为指导临床合理用药及控制医院感染提供依据。方法对该院2011年1月至2013年12月年临床送检标本进行细菌分离培养、鉴定和药敏试验。结果共检出肠球菌属细菌140株,屎肠球菌71株(50.7%),粪肠球菌60株(42.9%),其他肠球菌9株(6.4%),其中尿液99株(70.7%);粪肠球菌对青霉素、氨苄西林、红霉素的耐药率为15.0%、12.5%和75.0%,屎肠球菌对青霉素、氨苄西林、左氧氟沙星、环丙沙星、红霉素耐药率大于80.0%,粪肠球菌和屎肠球菌对万古霉素(5.0%、4.2%)、利奈唑胺(8.4%、1.4%)极度敏感,喹奴普丁/达福普丁对粪肠球菌耐药率(100.0%)高于屎肠球菌(26.7%),达托霉素无耐药菌株。结论肠球菌属以泌尿系统感染为主,屎肠球菌检出率略大于粪肠球菌,屎肠球菌对大多数抗菌药物耐药率高于粪肠球菌,喹奴普丁/达福普丁仅对屎肠球菌有较高敏感性,万古霉素、利奈唑胺、达托霉素对肠球菌属细菌保持极高敏感性。
Objective To explore the distribution and resistance characteristics of enteroco-ccus bacteria and offer guidance for rational administration and nosocomial infection.Methods Clinical specimens in our hospital from Jan 2011 to Dec 2013 were cultivated,then the identification and drug sensitivity test were carried out.Results 140 strains of enterococcus were detected,in which 99strains（70.7%）were from urine;Excrement enterococcus 71strains（50.7%）,60 in enterococcus strains（42.9%）,9other enterococcus strains（6.4%）;the drug of resistance rate of E.faecium to penicillin was 15.0%,ampicillin 12.5%,erythromycin 75.0%;while the drug of resistance rates of E.faecalis to penicillin,ampicillin,levofloxacin,ciprofloxacin and erythromycin were more than 80.0%;E.faecium and E.faecalis were acutely sensitive to vancomycin and linezolid,the drug of resistance rates of E.faecium and E.faecalis to vancomycin were 5.0%,4.2%respectively,linezolid were 8.4%,1.4%respectively,the drug of resistance rate of E.faecium to quinupristin/dalfopristin（100.0%）was more than E.faecalis（26.7%）,resistant strains of daptomycin have not been found so far.Conclusion Enterococcus was the predominant specie causing urinary tract infections,and the detection rate of E.faecalis slightly greater than E.faecium,the majority resistance to antimicrobial agents of E.faecalis were more than E.faecium;quinupristin、dalfopristin only has a higher sensitivity to E.faecalis;at the same time,vancomycin,linezolid and daptomycin keep high sensitivity to enterococcus.
出处
《检验医学与临床》
CAS
2015年第8期1081-1083,共3页
Laboratory Medicine and Clinic
关键词
肠球菌属
医院感染
抗菌药物
耐药性
enterococci
nosocomial infection
antibiotic
drug resistance
