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新诊断2型糖尿病患者无症状心肌缺血与糖化血红蛋白的关系研究 被引量:3

Relationship between asymptomatic myocardial ischemia and HbA1c in newly diagnosed type 2 diabetes mellitus
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摘要 目的探讨新诊断2型糖尿病患者无症状心肌缺血与糖化血红蛋白水平的关系。方法我们回顾性纳入了89例成功行冠状动脉CT血管成像检查的新诊断的2型糖尿病患者,分为合并无症状心肌缺血与未合并无症状心肌缺血2组,比较2组患者临床特征、糖化血红蛋白水平和血脂水平。结果新诊断的2型糖尿病患者中无症状心肌缺血患病率为27.0%(24/89),合并无症状心肌缺血组患者的糖化血红蛋白水平与未合并无症状心肌缺血组年龄差异有统计学意义[(61.8±9.5)岁比(53.6±8.7)岁,P<0.01],血清总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、三酰甘油、空腹血糖水平无明显差异(P>0.05)。2组糖化血红蛋白水平比较无统计学差异[(9.3±2.6)%比(10.3±2.6)%,P=0.107],Logistic回归校正年龄后,差异仍无统计学意义。结论新诊断2型糖尿病患者的无症状心肌缺血与糖化血红蛋白水平无明显相关。 Objective To determine the relationship between asymptomatic myocardial ischemia and Hb A1 c in newly diagnosed type 2 diabetes mellitus. Methods We retrospectively enrolled 89 patients with newly diagnosed type 2 diabetes who underwent cardiac CT showing no myocardiac ischemia symptoms. All patients were divided into newly diagnosed type 2 diabetes mellitus with asymptomatic myocardial ischemia group and newly diagnosed type 2 diabetes mellitus without asymptomatic myocardial ischemia group. Clinical characteristics and Hb A1 c were analyzed between the two groups. Results The incidence of asymptomatic myocardial ischemia in newly diagnosed type 2 diabetes mellitus was 27. 0%( 24 /89). Asymptomatic myocardial ischemia group did not show significant difference in Hb A1 c level compared with newly diagnosed type 2 diabetes mellitus without asymptomatic myocardial ischemia group[( 9. 3 ± 2. 6) % vs( 10. 3 ± 2. 6) %,P =0. 107]. And there were no significant differences in total cholesterol,triglycerides,high density lipoprotein cholesterol,low density lipoprotein cholesterol and fasting blood glucose. Conclusions There is no significant correlation between asymptomatic myocardial ischemia and Hb A1 c in newly diagnosed type 2 diabetes mellitus.
出处 《实用老年医学》 CAS 2015年第4期318-320,共3页 Practical Geriatrics
关键词 糖化血红蛋白 2型糖尿病 无症状心肌缺血 hemoglobin A1c type 2 diabetes mellitus asymptomatic myocardial ischemia
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