摘要
目的探讨低剂量多层螺旋CT灌注扫描在老年肺部肿瘤诊断和预后中的应用价值。方法选取经穿刺、病理检查证实为肺部恶性肿瘤老年患者38例和肺部良性肿瘤老年患者26例,治疗前后分别行低剂量多层螺旋CT灌注扫描,分析血容量、灌注值、强化幅度值和表面通透性在良/恶性肿瘤病变时及治疗前后的变化。结果良性肺部肿瘤平均灌注值、平均血容量、平均强化幅度值、表面通透性均显著小于恶性肺部肿瘤(t=6.5142,P<0.01;t=3.1245,P<0.01;t=4.4637,P<0.01;t=6.6436,P<0.01);良/恶性肺部肿瘤患者经治疗临床症状好转后各项指标均显著低于治疗前(t=9.1241,P<0.01;t=6.1241,P<0.01;t=7.4525,P<0.01;t=8.3456,P<0.01)。低剂量多层螺旋CT灌注扫描对老年肺部肿瘤的诊断及鉴别均具有较高的准确性,结合多项指标诊断可达到较好的预测评估效果。结论低剂量多层螺旋CT灌注扫描可以反映老年肺部肿瘤的供血情况,有助于准确筛查和鉴别良/恶性肿瘤状态。该方法也能够有效评价老年肺部肿瘤的治疗效果,为患者的后续治疗提供参考依据。
Objective To detect the value of diagnosis and therapy of low-dose multislice CT perfusion scanning in elderly lung cancer. Method 38 elderly malignant tumor cases and 26 elderly benign tumor cases conifrmed by biopsy were underwent low-dose multislice CT perfusion scanning before and after treatment. Analysed blood volume, perfusion values, strengthening the value of the amplitude and surface permeability changes before and after the treatment of benign and malignant tumors. Result Perfusion values, blood volume, strengthening the value of the amplitude and surface permeability in elderly benign tumor were signiifcantly lower than elderly malignant tumor （t=6.5142, P〈0.01;t=3.1245, P〈0.01;t=4.4637, P〈0.01;t=6.6436, P〈0.01）;the indexes of patients with bening/malignant lung tumor after treatment were signiifcantly lower than that before treatment （t=9.1241, P〈0.01;t=6.1241, P〈0.01;t=7.4525, P 〈 0.01; t = 8.3456, P 〈 0.01）. Low-dose multislice CT perfusion scanning in the diagnosis of elder pulmonary tumor and identification was higher accuracy, especially when combined with diagnostic index could be reached good estimate effect. Conclusion Low-dose multislice CT perfusion scanning could react elderly lung cancer blood supply, screen for elderly lung cancer, and evaluate the therapeutic efifcacy of lung elderly cancer. It can provide a reference for the follow-up treatment for patients.
出处
《中国医学前沿杂志（电子版）》
2015年第2期106-108,共3页
Chinese Journal of the Frontiers of Medical Science(Electronic Version)
