摘要
目的:为制订统一的中药材限量标准提供依据。方法:采用石墨炉原子吸收分光光度法测定77种、131批中药材中铅、镉的残留量,以中国、美国、德国、韩国等13个国家和地区的限量标准对测定结果进行统计、分析。结果:中药材中存在着不同程度的铅、镉污染,按2010年版《中国药典》判断,铅超标的批次占11.45%,超标的品种占18.18%;镉超标的批次占16.79%,超标的品种占20.78%;同一批次中药材存在两种元素同时超标的现象。按各国家和地区限量标准判断,得到的铅、镉超标率不同。与本文所列其他国家和地区比较,我国对铅执行更严格的限量标准,德国和法国对于镉的限量控制更加严格。结论:对中药材中重金属的研究还应深入开展。
OBJECTIVE：To provide reference for the formulation of limit standard of Chinese herbal medicines（CHM）.METHODS：Graphite furnace atomic absorption spectrometry was conducted to determine the lead and cadmium in 77 kinds and131 batches of CHM. The limit standard of 13 countries including China,USA,Germany and South Korea was used to statistically analyze the results. RESULTS：There were different degrees of lead and cadmium pollution in CHM. Judging by Chinese Pharmacopoeia（2010 edition）,lead in 11.45% of batches and 18.18% of kinds of CHM were excessive,cadmium in 16.79% of batches and20.78% of kinds of CHM were excessive;it was found that the elements were all excessive in a same batch of CHM. Judging by limit standards of different countries and regions,excessive rate of lead and cadmium were different. Compared with other countries and regions listed,the limit standard of lead in China was stricter and the limit control of cadmium in Germany and France was stricter. CONCLUSIONS：The study on heavy metals in CHM should go further.
出处
《中国药房》
CAS
北大核心
2015年第12期1678-1681,共4页
China Pharmacy
基金
"十一五"国家科技支撑计划项目(No.2008BAI55B02)
关键词
铅
镉
重金属
原子吸收分光光度法
中药材
Lead
Cadmium
Heavy metal
Graphite furnace atomic absorption spectrometry
Chinese herbal medicines
