摘要
人工髋关节置换术(total hip arthroplasty,THA)是目前髋关节终末疾病的重要治疗手段。术后常存在大量隐性失血,严重影响患者的术后康复。如何从根本上预防和减少THA术后隐性失血量,是亟待解决的问题。麻醉、年龄、性别、体重指数及抗凝药物的使用是THA手术失血的潜在因素,但其隐性失血的发生机制仍然不清。氨甲环酸在预防围手术期失血中的作用显著,今后有必要对隐性失血与纤溶机制的关联性进行证实,这对完善隐性失血的发生机制具有积极的意义。
Total hip arthroplasty（THA） is a vital therapeutic tool for hip terminal disease. Frequently, hidden blood loss exists in the postoperation, which seriously affect the postoperative rehabilitation of patients. It is urgent need to solve the problem that how to fundamentally prevent and reduce hidden blood loss after THA. Although THA has its own operational reason in blood loss, and also relates to a variety of risk factors, the mechanism of hidden blood loss is not clear. Tranexamic acid has a significant role in preventing perioperative blood loss, and the correlation of hidden blood loss and fibrinolytic mechanism would be confirm necessarily in the future, which will produce positive significance in completing the mechanism of hidden blood loss.
出处
《中国骨伤》
CAS
2015年第4期378-382,共5页
China Journal of Orthopaedics and Traumatology
基金
江苏省临床医学科技专项资助(编号:BL2012002)~~
关键词
关节成形术
置换
髋
手术后出血
综述文献
Arthroplasty,replacement,hip
Postoperative hemorrhage
Review literature
