摘要
目的探讨甲状腺相关眼病（TAO）对眼调节功能的影响。设计前瞻性病例系列。研究对象TAO患者25例，男性8例，女性17例，年龄18-40岁，平均（31．0±6．2）岁。选取相同年龄段和屈光度范围的正常人20例为对照组。方法对患者及正常对照组行显然验光、主观调节幅度检查，使用NidekAA．1人眼调节分析仪客观检测眼调节功能。主要指标调节幅度、调节反应量。结果TAO患者调节幅度（＋5．42±1．97D）比对照组（＋6．54±1．66D）低（t=-2．88，P=0．005）。调节功能客观检查显示17例（68％）患者存在调节功能异常，其中11例（44％）调节不足，4例（16％）调节不足伴调节紧张，2例（8％）调节紧张。结论TAO可引起眼调节功能的异常，其异常类型以调节不足为主。
Objective To explore the influences of thyroid associated ophthalmopathy （TAO） on the accommodative function of human eye. Design Prosprective case series. Participants 25 patients with TAO and 20 age and refraction matched healthy con- trois. The average age of the patients was 31.0± 6.2 years old （18-40 years）. Methods Direct refraction and subjective accommoda- tive amplitude test were performed for all the participants. Objective measurement of accommodative function was examined using the Nidek AA-1 accommodative analyzer. Main Outcome Measures Accommodative amplitude, accommodative response. Results In the subjective accommodative amplitude test, the accommodation amplitude of TAO patients （＋5.42±1.97 D） was lower than that of the controls （＋6.54±1.66 D） （t=-2.88, P=0.005）. In the objective accommodative function test, accommodative dysfunction happened in 17 cases （68%）, including 11 cases （44%） with accommodative lag; 4 cases （16%） with accommodative lag combined with accom- modative strain, and 3 cases （8%） with accommodative strain. Conclusion TAO can cause accommodative dysfimction, in which accomrnodative lag is most common.
出处
《眼科》
CAS
CSCD
北大核心
2015年第2期119-122,共4页
Ophthalmology in China
基金
北京市卫生系统高层次卫生技术人才基金(2011-3-046)
国家自然科学基金面上项目(10772124)
国家自然科学基金重点项目(11232013)
关键词
甲状腺相关眼病
睫状肌
调节功能
thyroid associated ophthalmopathy
ciliary muscle
accommodative function
