摘要
目的探讨氩氦刀冷冻消融术在姑息治疗韧带样纤维瘤中的临床应用价值。方法回顾性分析我院收治的5例术后复发的韧带样纤维瘤患者,采用CT引导经皮氩氦刀冷冻消融术进行治疗。对比术前及术后肿瘤大小、密度、强化方式、临床症状及血液学指标的变化,分析术后并发症的发生情况。结果 5例患者均顺利完成消融治疗。其中2例患者分别行3次及4次消融治疗,术后CT增强扫描示消融区明显液化坏死,边界清晰;残余肿瘤可见不同程度强化,术后12个月复查,5例患者肿瘤缓解率为80%(4/5);临床症状均有不同程度好转;术后并发症主要为疼痛、发热、软组织肿胀、排尿不畅、会阴部麻木等,1例患者出现皮肤冻伤;术后患者血液学指标急性期升高。结论 CT引导经皮氩氦刀冷冻消融术具有创伤小、能有效降低瘤负荷、缓解临床症状等特点,可作为姑息治疗术后复发韧带样纤维瘤的一种有效方法。
Objective To investigate the clinical value of palliative treatment of desmoid tumor by cryoablation. Methods Five cases with recurrent desmoid tumor were analyzed retrospectively, and CT-guided percutaneous cryoablation was done. The tumor size, density, changes in the way to strengthen, the clinical symptoms and hematological indexs before and after surgery were compared, and the occurrence of postoperative complications was analyzed. Results Five patients were successfully treated. Two patients were treated in 3 times and 4 times respectively, postoperative enhancement CT scan showed obvious liquefaction necrosis in ablation zone with clear boundaries, varying degrees strengthening was found in the residual tumor. The tumor response rate was 80% （4/5） after 12 months. Varying degrees of improvement was found in clinical symptoms. The main postoperative complications were pain, fever, soft tissue swelling, urination, perineal numbness; one patient appeared skin frostbite; hematological index of patients elevated in acute phase. Conclusion The characteristics of CT-guided percutaneous cryoablation are less traumaric, and can effectively reduce the tumor burden, relieve symptoms, it can be used as an effective method to treat recurrence desmoid tumor palliatively.
出处
《中国介入影像与治疗学》
CSCD
北大核心
2015年第4期214-217,共4页
Chinese Journal of Interventional Imaging and Therapy
关键词
冷冻疗法
纤维瘤
复发
Cryotherapy
Fibroma
Recurrence
